SCHEMBL5593283

SCHEMBL5593283

Cc1cc(F)c(-c2c(Cl)nc3ncnn3c2N2CCCC2C)cc1F

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDE2A O00408 19/20 0.40
EGLN2 Q96KS0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5593261 0.97 PDE2A (0.38) PDE2AEGLN2
SCHEMBL5593488 0.90 PDE2A (0.41) PDE2AEGLN2
SCHEMBL5593335 0.88 PDE2A (0.39) PDE2AEGLN2
SCHEMBL5593226 0.87 PDE2A (0.39) PDE2AEGLN2
SCHEMBL5593567 0.87 PDE2A (0.39) PDE2AEGLN2
SCHEMBL5593247 0.86 EGLN2 (0.46) PDE2AEGLN2
SCHEMBL5593485 0.85 PDE2A (0.37) PDE2AEGLN2
SCHEMBL5593427 0.85 ALDH1A1 (0.41) PDE2AEGLN2
SCHEMBL5593136 0.85 PDE2A (0.39) PDE2A
SCHEMBL8916445 0.84 TSHR (0.43) PDE2AEGLN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007099092-A1 SUBSTITUTED 6-PHENYL-7-AMINO[1,2,4]-TRIAZOLO[1,5-a]PYRIMIDINES AND THEIR USE FOR CONTROLLING PATHOGENIC FUNGI BASF SE (DE) 2007-09-07 WO claimed
WO-2007099092-A1 SUBSTITUTED 6-PHENYL-7-AMINO[1,2,4]-TRIAZOLO[1,5-a]PYRIMIDINES AND THEIR USE FOR CONTROLLING PATHOGENIC FUNGI BASF SE (DE) 2007-09-07 WO disclosed