Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.70 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.70 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.59 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.54 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenactropinium SCHEMBL29387827 | 1.00 | CHRM2 (0.70) | CHRM2CHRM1CHRNA7CHRM3LMNA | |
| Phenactropinium SCHEMBL308786 | 0.99 | CHRM2 (0.69) | CHRM2CHRM1CHRNA7CHRM3LMNA | |
| Methylhomatropine SCHEMBL17179980 | 0.83 | CHRM2 (1.00) | CHRM2CHRM1CHRM3LMNACYP2D6 | |
| Methylhomatropine SCHEMBL16784195 | 0.83 | CHRM2 (1.00) | CHRM2CHRM1CHRM3LMNACYP2D6 | |
| Methylhomatropine SCHEMBL30516140 | 0.83 | CHRM2 (1.00) | CHRM2CHRM1CHRM3LMNACYP2D6 | |
| Methylhomatropine SCHEMBL77827 | 0.82 | CHRM2 (0.97) | CHRM2CHRM1CHRM3LMNACYP2D6 | |
| Methylhomatropine SCHEMBL29555824 | 0.82 | CHRM2 (0.97) | CHRM2CHRM1CHRM3LMNACYP2D6 | |
| Methylhomatropine SCHEMBL20659943 | 0.82 | CHRM2 (0.97) | CHRM2CHRM1CHRM3LMNACYP2D6 | |
| Methylhomatropine SCHEMBL613580 | 0.82 | CHRM2 (0.97) | CHRM2CHRM1CHRM3LMNACYP2D6 | |
| Fentonium SCHEMBL251444 | 0.81 | CHRM2 (0.68) | CHRM2CHRM1CHRM3LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686448-A | Treatment of virus infections with ganglionic blocking agents | BALTECH, INC. (US) | 1997-11-11 | — | — | US | disclosed |
| US-4902720-A | Treatment of virus infections with quaternary ammonium compounds | BALTECH, INC., A CORP. OF LA | 1990-02-20 | — | — | US | disclosed |
| US-4898888-A | SUCH AS TETRAETHYLAMMONIUM OR HEXAMETHONIUM ION; HERPES SIMPLEX | BALTECH, INC. | 1990-02-06 | — | — | US | disclosed |