Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2697384 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1HTTGAADPP7 | |
| SCHEMBL2697385 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1HTTGAADPP7 | |
| SCHEMBL15739458 | 0.90 | POLB (0.47) | SMN1; SMN2NPC1HTTGAAHTR2A | |
| SCHEMBL29185139 | 0.90 | POLB (0.47) | SMN1; SMN2NPC1HTTGAAHTR2A | |
| SCHEMBL24337552 | 0.80 | EPHX1 (0.40) | SMN1; SMN2NPC1HTTGAADPP7 | |
| SCHEMBL20261888 | 0.80 | NPSR1 (0.42) | SMN1; SMN2NPC1HTTGAADPP7 | |
| SCHEMBL10181124 | 0.80 | NPSR1 (0.42) | SMN1; SMN2NPC1HTTGAADPP7 | |
| SCHEMBL30039829 | 0.78 | HTR2A (0.37) | SMN1; SMN2NPC1HTTGAAHTR2A | |
| SCHEMBL7569537 | 0.75 | DPP7 (0.48) | SMN1; SMN2NPC1HTTDPP7KDM4E | |
| SCHEMBL31269358 | 0.75 | HTR2A (0.35) | SMN1; SMN2NPC1HTTGAAHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654085-A | ADHERING SUBSTRATES BY APPLYING NONSAGGING POLYUREA ADHESIVE COMPRISING REACTION PRODUCT OF POLYMETHYLENEPOLYPHENYLENE POLYISOCYANATE WITH AMINOCROTONATE-TERMINATED POLYETHER AND LOW MOLECULAR WEIGHT DIAMINE, CURING | BAYER CORPORATION (US) | 1997-08-05 | — | — | US | disclosed |