Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6150412 | 0.87 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL6954823 | 0.82 | EDNRA (0.76) | EDNRAEDNRB | |
| SCHEMBL7222975 | 0.79 | EDNRA (0.76) | EDNRAEDNRB | |
| SCHEMBL6151477 | 0.79 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL6151347 | 0.74 | EDNRA (0.72) | EDNRAEDNRB | |
| SCHEMBL4630640 | 0.73 | EDNRA (0.71) | EDNRAEDNRB | |
| SCHEMBL7337364 | 0.73 | EDNRA (0.71) | EDNRAEDNRB | |
| SCHEMBL27465620 | 0.73 | EDNRA (0.71) | EDNRAEDNRB | |
| SCHEMBL6151672 | 0.72 | EDNRA (0.61) | EDNRAEDNRB | |
| SCHEMBL4631417 | 0.72 | EDNRA (1.00) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594021-A | VASOCONSTRICTORS | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1997-01-14 | — | — | US | claimed |
| CN-1636994-B | Process of preparing alkali metal salys of hydrophobic sulfonamides and alkali metal salt produced thereby | ENCYSIVE PHARMACEUTICALS INC | 2010-05-12 | — | — | CN | disclosed |
| CN-1636994-A | Process of preparing alkali metal salys of hydrophobic sulfonamides and alkali metal salt produced thereby | ENCYSIVE PHARMACEUTICALS INC (US) | 2005-07-13 | — | — | CN | disclosed |
| CN-1179961-C | Sulfonamides for the treatment of endothelin mediated diseases | ��ɪϣ����ҩ��˾ | 2004-12-15 | — | — | CN | disclosed |
| CN-1253560-A | Sulfonamides for the treatment of endothelin mediated diseases | TEXA BIOTECHNOLOGY CORP (US) | 2000-05-17 | — | — | CN | disclosed |