Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CASP2 | P42575 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308061 | 0.83 | PRMT1 (0.41) | PRMT1EPHX2ADRA1AKDM4EMAPK1 | |
| SCHEMBL9307831 | 0.83 | PRMT1 (0.41) | PRMT1EPHX2ADRA1AKDM4EMAPK1 | |
| SCHEMBL4141159 | 0.81 | DGKA (0.44) | MAPK1ALDH1A1LMNA | |
| SCHEMBL134788 | 0.81 | DGKA (0.44) | MAPK1ALDH1A1LMNA | |
| SCHEMBL338909 | 0.81 | DGKA (0.44) | MAPK1ALDH1A1LMNA | |
| SCHEMBL38542 | 0.81 | DGKA (0.44) | MAPK1ALDH1A1LMNA | |
| SCHEMBL10346810 | 0.81 | DGKA (0.44) | MAPK1ALDH1A1LMNA | |
| SCHEMBL20542 | 0.81 | DGKA (0.44) | MAPK1ALDH1A1LMNA | |
| SCHEMBL4662886 | 0.81 | DGKA (0.44) | MAPK1ALDH1A1LMNA | |
| SCHEMBL11065777 | 0.81 | DGKA (0.44) | MAPK1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5648521-A | DECYCLIZATION, OXIDATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-07-15 | — | — | US | disclosed |