Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | BCL9 | O00512 | 1/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MGLL | Q99685 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27355874 | 0.92 | HTR2A (0.60) | HTR2ABCL9CTNNB1GAAMAPT | |
| SCHEMBL7412947 | 0.90 | HTR2A (0.57) | HTR2ABCL9CTNNB1GAAMAPT | |
| SCHEMBL29654784 | 0.88 | HTR2A (0.52) | HTR2ABCL9CTNNB1GAAMAPT | |
| SCHEMBL21097204 | 0.83 | BCL9 (0.56) | HTR2ABCL9CTNNB1GAAMAPT | |
| SCHEMBL12375535 | 0.83 | BCL9 (0.56) | HTR2ABCL9CTNNB1GAAMAPT | |
| SCHEMBL21097658 | 0.83 | BCL9 (0.56) | HTR2ABCL9CTNNB1GAAMAPT | |
| SCHEMBL4390124 | 0.83 | HTR2A (0.50) | HTR2ABCL9CTNNB1GAAMAPT | |
| SCHEMBL4390129 | 0.83 | HTR2A (0.50) | HTR2ABCL9CTNNB1GAAMAPT | |
| SCHEMBL1242235 | 0.82 | HTR2A (0.54) | HTR2ABCL9CTNNB1GAAMAPT | |
| SCHEMBL8915974 | 0.82 | BCL9 (0.53) | HTR2ABCL9CTNNB1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684018-A | Acyloxyisopropyl carbamates as prodrugs for amine drugs | MERCK & CO., INC. (US) | 1997-11-04 | — | — | US | disclosed |
| WO-1996018605-A1 | ACYLOXYISOPROPYL CARBAMATES AS PRODRUGS FOR AMINE DRUGS | MERCK & CO., INC. (US) | 1996-06-20 | — | — | WO | disclosed |