Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | MIF | P14174 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | NAAA | Q02083 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1270016 | 0.94 | SIGMAR1 (0.59) | SIGMAR1MIFL3MBTL1NAAA | |
| SCHEMBL11107579 | 0.92 | SIGMAR1 (0.62) | SIGMAR1MIFL3MBTL1NAAA | |
| SCHEMBL11103198 | 0.92 | SIGMAR1 (0.62) | SIGMAR1MIFL3MBTL1NAAA | |
| SCHEMBL4874908 | 0.87 | NPC1 (0.52) | SIGMAR1KCNH2MIFL3MBTL1 | |
| SCHEMBL2074321 | 0.79 | SIGMAR1 (0.59) | SIGMAR1KMT2AMEN1KCNH2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL8171548 | 0.78 | SIGMAR1 (0.57) | SIGMAR1KMT2AMEN1KCNH2L3MBTL1 | |
| SCHEMBL10709659 | 0.76 | SIGMAR1 (0.67) | SIGMAR1KMT2AMEN1L3MBTL1HPGD | |
| SCHEMBL10752258 | 0.76 | SIGMAR1 (0.67) | SIGMAR1KMT2AMEN1L3MBTL1HPGD | |
| SCHEMBL4254894 | 0.75 | SIGMAR1 (1.00) | SIGMAR1KCNH2 | |
| SCHEMBL10395208 | 0.75 | SIGMAR1 (0.73) | SIGMAR1KMT2AMEN1L3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1205181-C | Matrix metalloproteinase inhibitors | LEO PHARMACEUTICAL PRODUOTS LT (DK) | 2005-06-08 | — | — | CN | disclosed |
| US-5616581-A | BACTERICIDES | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-04-01 | — | — | US | disclosed |
| US-5504082-A | BACTERICIDE FOR HELICOBACTER, ANTIULCER AGENT, GASTRIC ACIDSUPPRESSOR | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-04-02 | — | — | US | disclosed |
| EP-0644191-A1 | PYRIDINE COMPOUND AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-03-22 | — | — | EP | disclosed |