Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 19/20 | 0.73 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917019 | 0.95 | PTGS2 (0.73) | PTGS2PTGS1KIF11 | |
| SCHEMBL8915735 | 0.85 | PTGS2 (0.80) | PTGS2PTGS1 | |
| SCHEMBL8918341 | 0.85 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL8918347 | 0.85 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL8918427 | 0.84 | PTGS2 (0.74) | PTGS2PTGS1 | |
| SCHEMBL8915742 | 0.82 | PTGS2 (0.80) | PTGS2PTGS1 | |
| SCHEMBL8918839 | 0.82 | PTGS2 (0.62) | PTGS2PTGS1 | |
| SCHEMBL8918833 | 0.80 | PTGS2 (0.76) | PTGS2PTGS1 | |
| SCHEMBL8918835 | 0.80 | PTGS2 (0.76) | PTGS2PTGS1 | |
| SCHEMBL8918438 | 0.79 | PTGS2 (0.74) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677318-A | Diphenyl-1,2-3-thiadiazoles as anti-inflammatory agents | MERCK FROSST CANADA, INC. (CA) | 1997-10-14 | — | — | US | claimed |
| US-5677318-A | Diphenyl-1,2-3-thiadiazoles as anti-inflammatory agents | MERCK FROSST CANADA, INC. (CA) | 1997-10-14 | — | — | US | disclosed |