⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8908322 | 0.79 | NPSR1 (0.32) | — | |
| SCHEMBL19919844 | 0.77 | — | — | |
| SCHEMBL19564863 | 0.72 | — | — | |
| SCHEMBL7097916 | 0.72 | — | — | |
| SCHEMBL10154890 | 0.72 | — | — | |
| SCHEMBL13201632 | 0.72 | — | — | |
| SCHEMBL23547782 | 0.71 | TDP1 (0.31) | — | |
| SCHEMBL16407783 | 0.70 | — | — | |
| SCHEMBL7346043 | 0.70 | — | — | |
| SCHEMBL23389207 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022263573-A1 | ISOXAZOLINE PESTICIDES | ELANCO TIERGESUNDHEIT AG (US) | 2022-12-22 | — | — | WO | disclosed |
| WO-2022263530-A1 | (THI)OXAZOLINE PESTICIDES | ELANCO TIERGESUNDHEIT AG (US) | 2022-12-22 | — | — | WO | disclosed |
| US-20210188789-A1 | ISOXAZOLINE DERIVATIVES | ELANCO TIERGESUNDHEIT AG | 2021-06-24 | — | — | US | disclosed |
| US-10017499-B2 | Benzimidazole derivatives | ENANTA PHARMACEUTICALS, INC. (US) | 2018-07-10 | — | — | US | disclosed |
| US-20180057505-A1 | BICYCLIC HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF THE PAR-2 SIGNALING PATHWAY | VERTEX PHARMACEUTICALS INCORPORATED | 2018-03-01 | — | — | US | disclosed |
| US-20170114046-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | ENANTA PHARM INC (US) | 2017-04-27 | — | — | US | disclosed |
| US-8188132-B2 | Linked dibenzimidazole derivatives | ENANTA PHARMACEUTICALS, INC. (US) | 2012-05-29 | — | — | US | disclosed |
| US-20100221214-A1 | LINKED DIBENZIMIDAZOLE DERIVATIVES | ENANTA PHARMACEUTICALS, INC. | 2010-09-02 | — | — | US | disclosed |