⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7097916 | 0.78 | — | — | |
| SCHEMBL10729072 | 0.76 | — | — | |
| SCHEMBL7346043 | 0.76 | — | — | |
| SCHEMBL4531535 | 0.76 | — | — | |
| SCHEMBL6249700 | 0.74 | TSHR (0.43) | — | |
| SCHEMBL70980 | 0.74 | ALDH1A1 (0.43) | — | |
| SCHEMBL10772839 | 0.74 | ALDH1A1 (0.36) | — | |
| SCHEMBL17898496 | 0.72 | GAA (0.33) | — | |
| SCHEMBL8919021 | 0.72 | ALDH1A1 (0.35) | — | |
| SCHEMBL8917104 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219963-A1 | PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES | PFIZER INC. (US) | 2023-07-13 | — | — | US | disclosed |
| WO-2021127188-A1 | ISOXAZOLINE DERIVATIVES AS PESTICIDES | ELANCO TIERGESUNDHEIT AG (CH) | 2021-06-24 | — | — | WO | disclosed |
| US-9765087-B2 | Benzimidazole derivatives | ENANTA PHARMACEUTICALS, INC. (US) | 2017-09-19 | — | — | US | disclosed |
| US-20170114046-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | ENANTA PHARM INC (US) | 2017-04-27 | — | — | US | disclosed |
| US-20160289283-A1 | SELECTIVE PYY COMPOUNDS AND USES THEREOF | NOVO NORDISK (DK) | 2016-10-06 | — | — | US | disclosed |
| US-20160195532-A1 | Targeted Covalent Probes and Inhibitors of Proteins Containing Redox-Sensitive Cysteines | THE SCRIPPS RESEARCH INSTITUTE | 2016-07-07 | — | — | US | disclosed |
| US-9376387-B2 | Oxidisable pyridine derivatives, their preparation and use as anti-alzheimer agents | INSA INST NAT DES SCIENCES APPLIQUEES DE ROUEN (FR) | 2016-06-28 | — | — | US | disclosed |
| US-20150353493-A1 | OXIDISABLE PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE AS ANTI-ALZHEIMER AGENTS | INSA (INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE ROUEN (FR) | 2015-12-10 | — | — | US | disclosed |
| EP-2948429-A1 | OXIDISABLE PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE AS ANTI-ALZHEIMER AGENTS | INSA (Institut National des Sciences Appliquees) de Rouen (FR) | 2015-12-02 | — | — | EP | disclosed |
| CN-105121408-A | Oxidisable pyridine derivatives, preparation thereof and use as anti-alzheimer agents | INSA INST NAT DES SCIENCES APPLIQUEES DE ROUEN | 2015-12-02 | — | — | CN | disclosed |
| US-20140193363-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | ENANTA PHARMACEUTICALS, INC. (US) | 2014-07-10 | — | — | US | disclosed |
| US-8673954-B2 | Benzimidazole derivatives | ENANTA PHARMACEUTICALS, INC. (US) | 2014-03-18 | — | — | US | disclosed |
| US-8507522-B2 | Hepatitis C virus inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2013-08-13 | — | — | US | disclosed |
| US-8101643-B2 | Benzimidazole derivatives | ENANTA PHARMACEUTICALS, INC. (US) | 2012-01-24 | — | — | US | disclosed |
| US-20100260715-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2010-10-14 | — | — | US | disclosed |
| US-20100233122-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | ENANTA PHARMACEUTICALS, INC. | 2010-09-16 | — | — | US | disclosed |
| US-20100029903-A1 | Polypeptide Protracting Tags | NOVO NORDISK A/S (DK) | 2010-02-04 | — | — | US | disclosed |
| EP-0134934-B1 | 2-KETO-SULPHON AMIDES AND PROCESS FOR THEIR PRODUCTION | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-04 | — | — | EP | disclosed |
| US-4628109-A | 2-ketosulfonamides and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-12-09 | — | — | US | disclosed |
| EP-0134934-A1 | 2-Keto-sulphon amides and process for their production | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-03-27 | — | — | EP | disclosed |