Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRAS | P01112 | 13/20 | 0.54 |
| ▸ | ESR1 | P03372 | 13/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 13/20 | 0.54 |
| ▸ | TOP1 | P11387 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7328867 | 1.00 | HRAS (0.54) | HRASESR1ESR2TOP1KDM4E | |
| Hydrochloric Acid SCHEMBL6180839 | 0.99 | KDM4E (0.54) | HRASESR1ESR2TOP1KDM4E | |
| SCHEMBL4858229 | 0.91 | TOP1 (0.41) | HRASESR1ESR2TOP1KDM4E | |
| Hydrochloric Acid SCHEMBL4860217 | 0.90 | MAPT (0.42) | HRASESR1ESR2TOP1KDM4E | |
| SCHEMBL7127894 | 0.86 | HRAS (0.69) | HRASESR1ESR2TOP1KDM4E | |
| SCHEMBL4757631 | 0.85 | HRAS (0.55) | HRASESR1ESR2TOP1KDM4E | |
| SCHEMBL19493847 | 0.85 | HRAS (0.55) | HRASESR1ESR2TOP1KDM4E | |
| SCHEMBL27277513 | 0.84 | HRAS (0.54) | HRASESR1ESR2TOP1KDM4E | |
| SCHEMBL27272389 | 0.84 | HRAS (0.54) | HRASESR1ESR2TOP1KDM4E | |
| SCHEMBL27275903 | 0.84 | HRAS (0.54) | HRASESR1ESR2TOP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616606-A | DISTAMYCIN DERIVATIVES; DEACTIVATION OF NUCLEIC ACIDS BY BINDING WITH NO STERIC HINDRANCE PROBLEMS; HIV AND HEPATITUS VIRUS | SYNPHAR LABORATORIES, INC. (CA) | 1997-04-01 | — | — | US | disclosed |
| WO-1992013838-A1 | OLIGOPEPTIDE ANTIRETROVIRAL AGENTS | SYNPHAR LABORATORIES, INC. (CA) | 1992-08-20 | — | — | WO | disclosed |