Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 3/20 | 0.46 |
| ▸ | EDNRB | P24530 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17686902 | 0.87 | EDNRA (0.38) | EDNRAEDNRBMEN1KMT2AALDH1A1 | |
| SCHEMBL29401941 | 0.80 | EDNRA (0.39) | EDNRAEDNRBMEN1KMT2AALDH1A1 | |
| SCHEMBL63928 | 0.80 | EDNRA (0.39) | EDNRAEDNRBMEN1KMT2AALDH1A1 | |
| SCHEMBL17686905 | 0.78 | MEN1 (0.33) | EDNRAEDNRBMEN1KMT2AALOX15 | |
| Ammonia Solution, Strong SCHEMBL28107850 | 0.78 | EDNRA (0.38) | EDNRAEDNRBMEN1KMT2AALDH1A1 | |
| SCHEMBL28970647 | 0.78 | EDNRA (0.38) | EDNRAEDNRBMEN1KMT2AALDH1A1 | |
| SCHEMBL6272602 | 0.77 | EDNRA (0.37) | EDNRAEDNRBMEN1KMT2AALDH1A1 | |
| SCHEMBL9245713 | 0.75 | CYP2C9 (0.39) | EDNRAEDNRBMEN1KMT2ATSHR | |
| SCHEMBL11157224 | 0.75 | EDNRA (0.36) | EDNRAEDNRBMEN1KMT2AALDH1A1 | |
| SCHEMBL31141576 | 0.75 | TSHR (0.40) | EDNRAMEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591893-A | Process for the preparation of polycarboxylic acids and derivatives thereof | HOECHST AG (DE) | 1997-01-07 | — | — | US | claimed |
| US-20090061267-A1 | POWER DEVICE AND OXYGEN GENERATOR | BATTELLE MEMORIAL INSTITUTE (US) | 2009-03-05 | — | — | US | disclosed |
| US-20090061267-A1 | POWER DEVICE AND OXYGEN GENERATOR | BATTELLE MEMORIAL INSTITUTE (US) | 2009-03-05 | — | — | US | disclosed |
| US-5591893-A | Process for the preparation of polycarboxylic acids and derivatives thereof | HOECHST AG (DE) | 1997-01-07 | — | — | US | disclosed |
| EP-0513600-B1 | Process for preparing polycarboxylic acids and their derivatives | HOECHST AG (DE) | 1995-01-11 | — | — | EP | disclosed |
| EP-0513600-A2 | Process for preparing polycarboxylic acids and their derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-11-19 | — | — | EP | disclosed |