Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 3/20 | 0.37 |
| ▸ | EDNRB | P24530 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.30 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890229 | 0.83 | POLB (0.34) | ALDH1A1TDP1 | |
| SCHEMBL63928 | 0.80 | EDNRA (0.39) | EDNRAEDNRBMEN1KMT2AALDH1A1 | |
| SCHEMBL29401941 | 0.80 | EDNRA (0.39) | EDNRAEDNRBMEN1KMT2AALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL28107850 | 0.78 | EDNRA (0.38) | EDNRAEDNRBMEN1KMT2AALDH1A1 | |
| SCHEMBL28970647 | 0.78 | EDNRA (0.38) | EDNRAEDNRBMEN1KMT2AALDH1A1 | |
| SCHEMBL9115105 | 0.77 | FABP7 (0.44) | MEN1KMT2AALDH1A1TSHRTDP1 | |
| SCHEMBL631657 | 0.77 | HTR2A (0.31) | — | |
| SCHEMBL8917182 | 0.77 | EDNRA (0.46) | EDNRAEDNRBMEN1KMT2AALDH1A1 | |
| SCHEMBL3862739 | 0.71 | MAOA (0.32) | — | |
| SCHEMBL30661046 | 0.68 | HTR6 (0.33) | EDNRAEDNRBMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005113582-A1 | SUBSTITUTED ETHANE-1,2-DIAMINES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-12-01 | — | — | WO | claimed |
| WO-1995015325-A1 | IMIDAZOLYL-ALKENOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-06-08 | — | — | WO | claimed |
| WO-2005113582-A1 | SUBSTITUTED ETHANE-1,2-DIAMINES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-12-01 | — | — | WO | disclosed |
| WO-1995015325-A1 | IMIDAZOLYL-ALKENOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-06-08 | — | — | WO | disclosed |
| EP-0228299-A2 | Silver halide grains, lightsensitive photographic material containing the same and method for preparing silver halide photographic emulsion containing the same | KONICA CORPORATION (JP) | 1987-07-08 | — | — | EP | disclosed |
| EP-0171238-A2 | Silver halide grains, preparation thereof and light-sensitive photographic material containing said grains | KONICA CORPORATION (JP) | 1986-02-12 | — | — | EP | disclosed |