Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 2/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.33 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.32 |
| ▸ | HRH1 | P35367 | 4/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28140225 | 0.91 | METAP1 (0.37) | METAP1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL28025369 | 0.84 | METAP1 (0.37) | METAP1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL18261221 | 0.82 | METAP1 (0.46) | METAP1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9230716 | 0.78 | METAP1 (0.33) | METAP1MAPTMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL7609393 | 0.78 | PNMT (0.44) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL5684541 | 0.77 | METAP1 (0.42) | METAP1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL28265785 | 0.77 | METAP1 (0.42) | METAP1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL27845467 | 0.77 | METAP1 (0.42) | METAP1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL25878365 | 0.77 | METAP1 (0.42) | METAP1MAPTMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL9166044 | 0.76 | METAP1 (0.32) | METAP1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5668230-A | METALLOCENE WITH ETHYLENE BRIDGED FLUORENE UNITS, ALUMOXANE COCATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1997-09-16 | — | — | US | disclosed |