Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 3/20 | 0.44 |
| ▸ | KDR | P35968 | 3/20 | 0.44 |
| ▸ | OXTR | P30559 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8918938 | 0.87 | PDE3B (0.48) | MEN1KMT2ADRD4KDRMAPK14 | |
| Hydrochloric Acid SCHEMBL8921537 | 0.84 | PDE3B (0.53) | MEN1KMT2AMAPTOXTRALDH1A1 | |
| Hydrochloric Acid SCHEMBL7471638 | 0.83 | MEN1 (0.46) | MEN1KMT2ADRD4MAPK14CHIA | |
| SCHEMBL8919087 | 0.80 | DRD4 (0.42) | MEN1KMT2ADRD4CHIAGRIN2D | |
| Hydrochloric Acid SCHEMBL7470958 | 0.79 | HTR2B (0.46) | MEN1KMT2ADRD4MAPK14CHIA | |
| SCHEMBL7476032 | 0.78 | HRH4 (0.62) | MEN1KMT2AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL9206448 | 0.78 | DRD4 (0.48) | TSHRDRD4OXTRCHIAHPGD | |
| SCHEMBL7284840 | 0.77 | PDE3B (0.52) | MEN1KMT2ADRD4MAPK14GRIN2D | |
| Hydrochloric Acid SCHEMBL7470865 | 0.77 | KMT2A (0.45) | MEN1KMT2ADRD4CHIAALDH1A1 | |
| Hydrochloric Acid SCHEMBL8921226 | 0.77 | DRD4 (0.47) | TSHRDRD4OXTRCHIAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591751-A | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-07 | — | — | US | disclosed |
| EP-0636128-A1 | PIPERAZINOCARBONYLCARBOSTYRILS AS PERIPHERAL VASODILATORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-01 | — | — | EP | disclosed |
| WO-1994019339-A1 | PIPERAZINOCARBONYLCARBOSTYRILS AS PERIPHERAL VASODILATORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-01 | — | — | WO | disclosed |