⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL891653 | 0.91 | — | — | |
| SCHEMBL891685 | 0.86 | POLB (0.34) | — | |
| SCHEMBL891962 | 0.80 | LMNA (0.38) | — | |
| SCHEMBL891602 | 0.79 | POLB (0.34) | — | |
| SCHEMBL13161048 | 0.78 | POLA1 (0.47) | — | |
| SCHEMBL891252 | 0.77 | POLB (0.33) | — | |
| SCHEMBL891439 | 0.76 | POLB (0.35) | — | |
| SCHEMBL891694 | 0.76 | LMNA (0.38) | — | |
| SCHEMBL891530 | 0.74 | KMT2A (0.31) | — | |
| SCHEMBL891417 | 0.74 | POLB (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120082645-A1 | 2'-C-METHYL-RIBOFURANOSYL CYTIDINE PRODRUGS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | XENOPORT, INC. (US) | 2012-04-05 | — | — | US | claimed |
| US-8058260-B2 | 2′-C-methyl-ribofuranosyl cytidine prodrugs, pharmaceutical compositions and uses thereof | XENOPORT, INC. (US) | 2011-11-15 | — | — | US | claimed |
| US-20070270374-A1 | 2'-C-Methyl-Ribofuranosyl Cytidine Prodrugs, Pharmaceutical Compositions and Uses Thereof | XENOPORT, INC. | 2007-11-22 | — | — | US | claimed |
| US-20120082645-A1 | 2'-C-METHYL-RIBOFURANOSYL CYTIDINE PRODRUGS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | XENOPORT, INC. (US) | 2012-04-05 | — | — | US | disclosed |
| US-8058260-B2 | 2′-C-methyl-ribofuranosyl cytidine prodrugs, pharmaceutical compositions and uses thereof | XENOPORT, INC. (US) | 2011-11-15 | — | — | US | disclosed |
| US-20070270374-A1 | 2'-C-Methyl-Ribofuranosyl Cytidine Prodrugs, Pharmaceutical Compositions and Uses Thereof | XENOPORT, INC. | 2007-11-22 | — | — | US | disclosed |