Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13386614 | 0.72 | BTK (0.38) | KMT2A | |
| SCHEMBL13386613 | 0.72 | BTK (0.38) | KMT2A | |
| SCHEMBL17841989 | 0.71 | NR1H2 (0.43) | MEN1KMT2A | |
| SCHEMBL4796487 | 0.70 | EPHX1 (0.45) | — | |
| SCHEMBL4800986 | 0.70 | EPHX1 (0.45) | — | |
| SCHEMBL21906219 | 0.70 | — | — | |
| SCHEMBL31501822 | 0.70 | BRD4 (0.35) | — | |
| SCHEMBL10332285 | 0.69 | MEN1 (0.41) | MEN1KMT2A | |
| SCHEMBL16862491 | 0.69 | ATM (0.31) | — | |
| SCHEMBL24735973 | 0.68 | ACHE (0.41) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5625075-A | Metal radionuclide chelating compounds for improved chelation kinetics | NEORX CORPORATION (US) | 1997-04-29 | — | — | US | disclosed |
| US-5436352-A | Metal radionuclide chelating compounds for improved chelation kinetics | NEORX CORPORATION (US) | 1995-07-25 | — | — | US | disclosed |
| EP-0344724-B1 | METAL RADIONUCLIDE CHELATING COMPOUNDS FOR IMPROVED CHELATION KINETICS | NEORX CORPORATION (US) | 1993-08-11 | — | — | EP | disclosed |
| US-5075099-A | Metal radionuclide chelating compounds for improved chelation kinetics | NEORX CORPORATION (US) | 1991-12-24 | — | — | US | disclosed |
| EP-0344724-A2 | Metal radionuclide chelating compounds for improved chelation kinetics | NEORX CORPORATION (US) | 1989-12-06 | — | — | EP | disclosed |