Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | NAMPT | P43490 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4528384 | 0.85 | CA2 (0.46) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL4526320 | 0.85 | CA2 (0.46) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL25961260 | 0.83 | CA2 (0.44) | CA2TSHRALDH1A1NPSR1TMEM97 | |
| SCHEMBL15786354 | 0.83 | CA2 (0.44) | CA2TSHRALDH1A1NPSR1TMEM97 | |
| SCHEMBL28924707 | 0.83 | CA2 (0.44) | CA2TSHRALDH1A1NPSR1TMEM97 | |
| SCHEMBL21135291 | 0.82 | CA2 (0.48) | CA2TSHRLMNAALDH1A1NPSR1 | |
| SCHEMBL24326321 | 0.80 | TSHR (0.42) | CA2TSHRALDH1A1NPSR1TMEM97 | |
| SCHEMBL1842907 | 0.80 | TSHR (0.42) | CA2TSHRALDH1A1NPSR1TMEM97 | |
| SCHEMBL8257934 | 0.78 | CTDSP1 (0.41) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL10391550 | 0.78 | CA2 (0.45) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696248-A | GENE EXPRESSION INHIBITOR, AS PROBES FOR DETECTING NUCLEIC ACIDS, AS VIRICIDES TREATING VIRAL DISEASE CAUSED BY HTLV, INFLUENZA, HEPATITIS VIRUS, PAPILLOMA VIRUS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-09 | — | — | US | disclosed |