Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 17/20 | 0.69 |
| ▸ | F2 | P00734 | 9/20 | 0.66 |
| ▸ | F10 | P00742 | 3/20 | 0.60 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628345 | 0.85 | F7 (0.76) | F7F2F10ITGB3ITGA2B | |
| SCHEMBL7345475 | 0.83 | ITGB3 (0.80) | ITGB3ITGA2B | |
| SCHEMBL4426386 | 0.82 | F7 (0.64) | F7F2F10ITGB3ITGA2B | |
| SCHEMBL7381831 | 0.82 | F7 (0.62) | F7F2F10ITGB3ITGA2B | |
| SCHEMBL4419447 | 0.81 | F7 (1.00) | F7F2F10 | |
| SCHEMBL235788 | 0.80 | F7 (1.00) | F7F2F10 | |
| SCHEMBL13936352 | 0.80 | F7 (1.00) | F7F2F10 | |
| SCHEMBL7379448 | 0.79 | ITGB3 (0.74) | F7F2F10ITGB3ITGA2B | |
| SCHEMBL9389691 | 0.79 | ITGB3 (0.77) | F7F2F10ITGB3ITGA2B | |
| SCHEMBL7385792 | 0.79 | ITGB3 (0.77) | F7F2F10ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624956-A | Urea derivatives useful as platelet aggregation inhibitors | THE MONSANTO COMPANY (US) | 1997-04-29 | — | — | US | claimed |
| WO-1994017041-A1 | AMIDINOPHENYL SUBSTITUTED UREA, THIOUREA OR GUANIDINO DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-08-04 | — | — | WO | claimed |
| US-5624956-A | Urea derivatives useful as platelet aggregation inhibitors | THE MONSANTO COMPANY (US) | 1997-04-29 | — | — | US | disclosed |
| US-5475025-A | Urea derivatives useful as platelet aggregation inhibitors | THE MONSANTO COMPANY (US) | 1995-12-12 | — | — | US | disclosed |