Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8578095 | 0.85 | AKR1C3 (0.55) | MAPTAKR1C3GAAALDH1A1KMT2A | |
| SCHEMBL31005115 | 0.84 | AKR1C3 (0.50) | MAPTAKR1C3GAAALDH1A1KMT2A | |
| SCHEMBL26110213 | 0.83 | AKR1C3 (0.48) | MAPTAKR1C3GAAALDH1A1KMT2A | |
| SCHEMBL11755306 | 0.83 | AKR1C3 (0.48) | MAPTAKR1C3GAAALDH1A1KMT2A | |
| SCHEMBL2960122 | 0.82 | ALDH1A1 (0.57) | KDM4EALOX15HSD17B10GAAALDH1A1 | |
| SCHEMBL11754962 | 0.81 | AKR1C3 (0.47) | MAPTHSD17B10AKR1C3GAAALDH1A1 | |
| SCHEMBL11758277 | 0.81 | AKR1C3 (0.47) | MAPTAKR1C3GAAALDH1A1KMT2A | |
| SCHEMBL11761776 | 0.81 | AKR1C3 (0.56) | MAPTHSD17B10AKR1C3GAAALDH1A1 | |
| SCHEMBL11760101 | 0.78 | AKR1C3 (0.43) | MAPTAKR1C3GAAALDH1A1KMT2A | |
| SCHEMBL11756096 | 0.78 | AKR1C3 (0.43) | MAPTMAPK1AKR1C3GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684131-A | Substituted benzhydrylamines as handles for solid phase peptide synthesis | LEBL MICHAL (US) | 1997-11-04 | — | — | US | disclosed |