Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 7/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917602 | 0.84 | ALDH1A1 (0.48) | BPTFALDH1A1L3MBTL1MAPTKDM4E | |
| SCHEMBL8917746 | 0.83 | ALDH1A1 (0.45) | BPTFALDH1A1L3MBTL1MAPTKDM4E | |
| SCHEMBL8918691 | 0.82 | ALDH1A1 (0.46) | BPTFALDH1A1L3MBTL1MAPTKDM4E | |
| SCHEMBL8991837 | 0.81 | ALDH1A1 (0.45) | BPTFALDH1A1L3MBTL1MAPTKDM4E | |
| SCHEMBL8915764 | 0.80 | BPTF (0.48) | BPTFALDH1A1L3MBTL1MAPTKDM4E | |
| SCHEMBL8916936 | 0.75 | BPTF (0.46) | BPTFALDH1A1L3MBTL1MAPTKDM4E | |
| SCHEMBL8916773 | 0.74 | BPTF (0.45) | BPTFALDH1A1L3MBTL1MAPTKDM4E | |
| SCHEMBL8918078 | 0.73 | ALDH1A1 (0.45) | BPTFALDH1A1L3MBTL1MAPTKDM4E | |
| SCHEMBL8916698 | 0.71 | BPTF (0.39) | BPTFALDH1A1L3MBTL1MAPTKDM4E | |
| SCHEMBL8916463 | 0.70 | ALDH1A1 (0.50) | BPTFALDH1A1L3MBTL1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0596125-A1 | CONDENSED THIOPHENE COMPOUND AND PHARMACEUTICAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-05-11 | — | — | EP | disclosed |