SCHEMBL8918066

SCHEMBL8918066

NC(=O)c1c(Cl)c(Cl)c(Cl)c(Cl)c1C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.42
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
DPP4 P27487 1/20 0.34
POLB P06746 2/20 0.33
SIRT6 Q8N6T7 1/20 0.32
CYP3A4 P08684 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
CYP1A2 P05177 2/20 0.31
HSD17B10 Q99714 2/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
HIF1A Q16665 1/20 0.31
ALDH1A1 P00352 2/20 0.30
KDM4E B2RXH2 1/20 0.30
MAPK1 P28482 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
ACHE P22303 1/20 0.30
F2 P00734 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1456243 0.89 CES2 (0.42) HTTCES2CES1POLBSIRT6
SCHEMBL27772 0.86 HTT (0.50) HTTCES2CES1DPP4CYP3A4
SCHEMBL29431520 0.86 HTT (0.50) HTTCES2CES1DPP4CYP3A4
SCHEMBL5693960 0.83 HTT (0.48) HTTCES2CES1DPP4CYP3A4
Hydrochloric Acid SCHEMBL10668016 0.83 HTT (0.48) HTTCES2CES1DPP4CYP3A4
SCHEMBL10804236 0.83 CES2 (0.42) HTTCES2CES1POLBSIRT6
Fluoride SCHEMBL6441994 0.83 HTT (0.54) HTTCES2CES1DPP4CYP3A4
SCHEMBL3630379 0.83 HTT (0.48) HTTCES2CES1DPP4CYP3A4
Hydrochloric Acid SCHEMBL10715453 0.83 HTT (0.48) HTTCES2CES1DPP4CYP3A4
SCHEMBL6903601 0.83 HTT (0.48) HTTCES2CES1DPP4CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103450013-A Industrial preparation method of 2,4,5-trifluoro-3-methoxybenzoyl chloride YUEYANG YETOP FINE CHEMICAL CO LTD 2013-12-18 CN claimed
US-4318919-A Combating bacteria with tetrachlorophthalamic acids BAYER AKTIENGESELLSCHAFT (DE) 1982-03-09 US claimed
EP-0024016-B1 TETRACHLOROPHTHALAMIC ACIDS, PROCESS FOR THEIR PREPARATION AND THEIR BACTERICIDAL USE BAYER AG (DE) 1982-02-24 EP claimed
EP-0024016-A1 Tetrachlorophthalamic acids, process for their preparation and their bactericidal use BAYER AG (DE) 1981-02-18 EP claimed
CN-105829485-B Photocurable composition with adhesiveness 思美定株式会社 2018-10-12 CN disclosed
CN-103450013-B Industrial preparation method of 2,4,5-trifluoro-3-methoxybenzoyl chloride YUEYANG YETOP FINE CHEMICAL CO LTD 2015-06-17 CN disclosed
CN-103450013-A Industrial preparation method of 2,4,5-trifluoro-3-methoxybenzoyl chloride YUEYANG YETOP FINE CHEMICAL CO LTD 2013-12-18 CN disclosed
US-5675002-A PURIFYING PHTHALOCYANINE PIGMENTS IN WATER BY TREATING WITH A TWO-PHASE SYSTEM COMPRISING A WATER-IMMISCIBLE WETTING PHASE AND A WATER/ACID PHASE TO DISSOLVE IMPURITIES BASF AKTIENGESELLSCHAFT (DE) 1997-10-07 US disclosed
EP-0716046-A1 Oxydation process of organic chloride compounds in waste waters BASF AKTIENGESELLSCHAFT (DE) 1996-06-12 EP disclosed
EP-0651776-A1 METHOD OF PURIFYING SOLID HYDROPHOBIC SUBSTANCES BASF Aktiengesellschaft (DE) 1995-05-10 EP disclosed
WO-1994002550-A1 METHOD OF PURIFYING SOLID HYDROPHOBIC SUBSTANCES BASF AKTIENGESELLSCHAFT (DE) 1994-02-03 WO disclosed
EP-0482668-B1 HEAT SENSITIVE RECORDING MATERIAL KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1993-08-04 EP disclosed
EP-0109818-A2 Process for the preparation of penicillin and cephalosporin sulfones ELI LILLY AND COMPANY (US) 1984-05-30 EP disclosed
US-4348411-A Combating bacteria with halogenomethylsulphonylphenyl-phthalamic acids BAYER AKTIENGESELLSCHAFT (DE) 1982-09-07 US disclosed
US-4318919-A Combating bacteria with tetrachlorophthalamic acids BAYER AKTIENGESELLSCHAFT (DE) 1982-03-09 US disclosed
US-4318919-A Combating bacteria with tetrachlorophthalamic acids BAYER AKTIENGESELLSCHAFT (DE) 1982-03-09 US disclosed
US-4318919-A Combating bacteria with tetrachlorophthalamic acids BAYER AKTIENGESELLSCHAFT (DE) 1982-03-09 US disclosed
US-4273674-A HALOGENATED PHTHALIMIDES GENERAL ELECTRIC COMPANY (US) 1981-06-16 US disclosed
EP-0024016-A1 Tetrachlorophthalamic acids, process for their preparation and their bactericidal use BAYER AG (DE) 1981-02-18 EP disclosed
US-4204428-A Thermal detection system for failure in electrical apparatus and thermal detecting paint compositions GENERAL ELECTRIC COMPANY (US) 1980-05-27 US disclosed