Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.33 |
| ▸ | GABRE | P78334 | 2/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.33 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13693058 | 0.77 | ADORA2A (0.39) | MEN1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL13066536 | 0.77 | KDM4E (0.38) | MEN1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL739581 | 0.75 | MEN1 (0.34) | MEN1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL31612964 | 0.75 | IKBKB (0.32) | POLB | |
| SCHEMBL8916919 | 0.75 | MEN1 (0.32) | MEN1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL13184297 | 0.73 | MEN1 (0.32) | MEN1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL14039851 | 0.72 | CYP2C9 (0.38) | MEN1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL17542481 | 0.72 | MAPT (0.39) | MEN1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL14201637 | 0.72 | KMT2A (0.36) | MEN1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL13066182 | 0.72 | MEN1 (0.33) | MEN1CYP1A2CYP2C9CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5668278-A | HERBICIDES AND CHEMICAL INTERMEDIATES | HOESCHST SCHERING AGREVO GMBH (DE) | 1997-09-16 | — | — | US | disclosed |
| US-5556986-A | CHEMICAL INTERMEDIATES FOR PYRAZOLYLPYRAZOLES AS HERBICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1996-09-17 | — | — | US | disclosed |
| EP-0643700-B1 | NEW SUBSTITUTED PYRAZOLYLPYRAZOLES, PROCESSES FOR THEIR PREPARATION, AS WELL AS INTERMEDIATES, AND THEIR USE AS HERBICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1996-09-11 | — | — | EP | disclosed |
| US-5405829-A | Substituted pyrazolypyrazoles and their use as herbicides | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-04-11 | — | — | US | disclosed |
| EP-0643700-A1 | NEW SUBSTITUTED PYRAZOLYLPYRAZOLES, PROCESSES FOR THEIR PREPARATION, AS WELL AS INTERMEDIATES, AND THEIR USE AS HERBICIDES. | SCHERING AG (DE) | 1995-03-22 | — | — | EP | disclosed |
| WO-1993010100-A1 | NEW SUBSTITUTED PYRAZOLYLPYRAZOLES, PROCESSES FOR THEIR PREPARATION, AS WELL AS INTERMEDIATES, AND THEIR USE AS HERBICIDES | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-05-27 | — | — | WO | disclosed |
| EP-0542388-A1 | New substituted pyrazolylpyrazoles, processes for their preparation, as well as intermediates, and their use as herbicides | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-05-19 | — | — | EP | disclosed |