SCHEMBL31612964

SCHEMBL31612964

Cn1nc(N)c(Br)c1C(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
IKBKB O14920 1/20 0.32
MAP3K14 Q99558 1/20 0.32
POLB P06746 1/20 0.32
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13715651 0.77 SMN1; SMN2 (0.37) GAA
SCHEMBL8918080 0.75 MEN1 (0.34) POLB
SCHEMBL10473360 0.75 GAA (0.31) GAA
SCHEMBL31612983 0.75 MAP3K12 (0.33) IKBKBMAP3K14
SCHEMBL31613005 0.75 PTGS2 (0.35) IKBKBMAP3K14
SCHEMBL31612970 0.73 CNR1 (0.35)
SCHEMBL31612965 0.73
SCHEMBL24378081 0.72 GAA (0.36) GAA
SCHEMBL31612966 0.71 ADORA3 (0.31)
SCHEMBL19635907 0.71 IDO1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025119300-A1 MYT1 KINASE INHIBITOR COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF 广东东阳光药业股份有限公司 2025-06-12 WO disclosed
CN-120118088-A Myt1 kinase inhibitor compounds, pharmaceutical compositions thereof and uses thereof 广东东阳光药业股份有限公司 2025-06-10 CN disclosed