SCHEMBL8918233

SCHEMBL8918233

CC=CC=CCc1cnc(Cl)c(C(N)=O)c1CC

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
JAK3 P52333 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8918128 0.86 USP7 (0.32)
SCHEMBL8918193 0.86
SCHEMBL8922863 0.84 GABRP (0.31)
SCHEMBL8920425 0.83 POLB (0.34) POLB
SCHEMBL28899823 0.82 POLB (0.39) POLB
SCHEMBL27980296 0.73 POLB (0.41) POLB
SCHEMBL8920240 0.70
SCHEMBL8919038 0.68 POLB (0.38) POLB
SCHEMBL8918638 0.66 SMN1; SMN2 (0.40) POLB
SCHEMBL28192594 0.65 PARP1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5691366-A UNSATURATED NITRO OXIME FORMED BY REACTION OF DINITROGEN TRIOXIDE WITH DIOLEFIN ETHER, SULFIDE OR AMINE TO BE USED AS VASODILATORS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-11-25 US disclosed