Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 5/20 | 0.36 |
| ▸ | CES2 | O00748 | 3/20 | 0.35 |
| ▸ | CES1 | P23141 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8920660 | 0.96 | NPC1 (0.35) | KCNH2S1PR5CES2CES1NPC1 | |
| SCHEMBL8073703 | 0.92 | KCNH2 (0.39) | KCNH2S1PR5CES2CES1S1PR1 | |
| SCHEMBL8073707 | 0.91 | KCNH2 (0.41) | KCNH2S1PR5CES2CES1S1PR1 | |
| SCHEMBL8917063 | 0.91 | NPC1 (0.37) | CES2CES1NPC1RAB9APOLB | |
| SCHEMBL8916577 | 0.85 | KDM4E (0.33) | S1PR5NPC1RAB9AKMT2APOLB | |
| SCHEMBL8917942 | 0.85 | KCNH2 (0.33) | KCNH2MEN1KMT2A | |
| SCHEMBL7767031 | 0.83 | KCNH2 (0.33) | KCNH2 | |
| SCHEMBL7767036 | 0.83 | KCNH2 (0.33) | KCNH2 | |
| SCHEMBL7755593 | 0.82 | KCNH2 (0.32) | KCNH2MEN1KMT2APOLB | |
| SCHEMBL8916925 | 0.81 | SPHK1 (0.31) | KCNH2RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5595686-A | Silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-01-21 | — | — | US | disclosed |
| EP-0699683-A1 | Novel silacyclohexane compounds a liquid crystal composition comprising the same and a liquid crystal device comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-03-06 | — | — | EP | disclosed |