Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 3/20 | 0.39 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 6/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8073707 | 0.99 | KCNH2 (0.41) | KCNH2CES2CES1S1PR5S1PR1 | |
| SCHEMBL8918246 | 0.92 | KCNH2 (0.36) | KCNH2CES2CES1S1PR5S1PR1 | |
| SCHEMBL8920660 | 0.88 | NPC1 (0.35) | KCNH2CES2CES1S1PR5S1PR1 | |
| SCHEMBL8079201 | 0.86 | POLB (0.37) | POLBL3MBTL1CASP1CASP7 | |
| SCHEMBL8073971 | 0.84 | KDM4E (0.36) | S1PR5POLBPPARGL3MBTL1 | |
| SCHEMBL8917063 | 0.82 | NPC1 (0.37) | CES2CES1POLBL3MBTL1CASP1 | |
| SCHEMBL8074187 | 0.81 | POLB (0.34) | S1PR5S1PR1POLBL3MBTL1CASP1 | |
| SCHEMBL8077099 | 0.81 | POLB (0.35) | POLBL3MBTL1 | |
| SCHEMBL8073314 | 0.80 | PPARG (0.37) | S1PR5S1PR1POLBPPARGL3MBTL1 | |
| SCHEMBL9272010 | 0.80 | LMNA (0.33) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708106-B1 | Novel silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition | SHINETSU CHEMICAL CO (JP) | 2000-08-09 | — | — | EP | disclosed |
| US-5650092-A | LIQUID CRYSTAL COMPOUNDS FOR DEVICES WITH ESTER COMPOUNDS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-07-22 | — | — | US | disclosed |
| EP-0708106-A1 | Novel silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-04-24 | — | — | EP | disclosed |