Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.51 |
| ▸ | PNP | P00491 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TYMP | P19971 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8918615 | 1.00 | ADRB1 (0.51) | ADRB1DNMT1PNPLMNATP53 | |
| SCHEMBL8506519 | 0.87 | CYP1A2 (0.55) | ADRB1DNMT1PNPLMNATP53 | |
| SCHEMBL6846752 | 0.84 | ADRB1 (0.53) | ADRB1DNMT1PNPLMNATP53 | |
| SCHEMBL7272046 | 0.81 | DNMT1 (0.54) | ADRB1DNMT1PNPLMNATP53 | |
| SCHEMBL9063510 | 0.80 | ADRB1 (0.61) | ADRB1DNMT1PNPLMNATP53 | |
| SCHEMBL31685458 | 0.79 | ADRB1 (0.60) | ADRB1DNMT1PNPLMNATP53 | |
| SCHEMBL29260171 | 0.79 | ADRB1 (0.60) | ADRB1DNMT1PNPLMNATP53 | |
| SCHEMBL5360845 | 0.76 | CYP1A2 (0.71) | ADRB1DNMT1PNPLMNATP53 | |
| SCHEMBL9017497 | 0.76 | PNP (0.47) | ADRB1DNMT1PNPLMNATP53 | |
| SCHEMBL6848231 | 0.76 | ADRB1 (0.56) | ADRB1DNMT1PNPLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5623068-A | Synthesis of DNA using substituted phenylacetyl-protected nucleotides | BECKMAN INSTRUMENTS, INC. (US) | 1997-04-22 | — | — | US | disclosed |