Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | STAT6 | P42226 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13086353 | 0.85 | MEN1 (0.48) | KLK7OPRD1STAT6 | |
| SCHEMBL13086597 | 0.85 | MEN1 (0.48) | KLK7OPRD1STAT6 | |
| SCHEMBL6012084 | 0.85 | MEN1 (0.48) | KLK7OPRD1STAT6 | |
| SCHEMBL13086595 | 0.84 | MEN1 (0.49) | KLK7OPRD1STAT6 | |
| SCHEMBL13086758 | 0.83 | MEN1 (0.50) | KLK7OPRD1STAT6 | |
| SCHEMBL2689602 | 0.81 | KLK7 (0.49) | NR1H2NR1H3KLK7OPRD1KDM1A | |
| SCHEMBL3046705 | 0.81 | KLK7 (0.49) | NR1H2NR1H3KLK7OPRD1KDM1A | |
| SCHEMBL13086596 | 0.81 | KLK7 (0.49) | NR1H2NR1H3KLK7OPRD1KDM1A | |
| SCHEMBL6012057 | 0.80 | ATM (0.44) | KLK7OPRD1KDM1A | |
| SCHEMBL8917522 | 0.80 | ACE2 (0.42) | ACE2NR1H2NR1H3ACEKLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686565-A | ANTIINFLAMMATORY AGENTS | SCIOS INC. (US) | 1997-11-11 | — | — | US | disclosed |
| US-5552383-A | ANALGESIC, ANTIINFLAMMATORY FOR WOUNDS | SCIOS NOVA INC. (US) | 1996-09-03 | — | — | US | disclosed |