Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 6/20 | 0.42 |
| ▸ | STAT6 | P42226 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 2/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8919439 | 0.91 | ACE2 (0.44) | ACE2STAT6ACEKLK7MEN1 | |
| SCHEMBL3045671 | 0.86 | FKBP1A (0.45) | STAT6ACEKLK7MEN1ALDH1A1 | |
| SCHEMBL3045668 | 0.86 | FKBP1A (0.45) | STAT6ACEKLK7MEN1ALDH1A1 | |
| SCHEMBL3046636 | 0.85 | FKBP1A (0.45) | STAT6KLK7MEN1ALDH1A1LMNA | |
| SCHEMBL3046635 | 0.85 | FKBP1A (0.45) | STAT6KLK7MEN1ALDH1A1LMNA | |
| SCHEMBL3046386 | 0.84 | STAT6 (0.50) | STAT6ACEKLK7MEN1ALDH1A1 | |
| SCHEMBL3046383 | 0.84 | STAT6 (0.50) | STAT6ACEKLK7MEN1ALDH1A1 | |
| SCHEMBL3051710 | 0.84 | KLK7 (0.47) | ACEKLK7MEN1ALDH1A1LMNA | |
| SCHEMBL3051711 | 0.84 | KLK7 (0.47) | ACEKLK7MEN1ALDH1A1LMNA | |
| SCHEMBL8918708 | 0.80 | ACE2 (0.44) | ACE2STAT6ACEKLK7KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686565-A | ANTIINFLAMMATORY AGENTS | SCIOS INC. (US) | 1997-11-11 | — | — | US | disclosed |