Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NOS1 | P29475 | 2/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2147268 | 0.98 | ATM (0.51) | ATML3MBTL1NOS1ITGB3ITGA2B | |
| SCHEMBL8432804 | 0.91 | DRD4 (0.50) | ATML3MBTL1NOS1DRD4DRD2 | |
| SCHEMBL17465617 | 0.89 | ATM (0.58) | ATML3MBTL1NOS1DRD4DRD2 | |
| SCHEMBL7898603 | 0.89 | ATM (0.58) | ATML3MBTL1NOS1DRD4DRD2 | |
| SCHEMBL17445905 | 0.87 | ATM (0.60) | ATML3MBTL1NOS1DRD4DRD2 | |
| SCHEMBL7679458 | 0.87 | LSS (0.61) | L3MBTL1ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL7686335 | 0.85 | LSS (0.60) | L3MBTL1ITGB3ITGA2B | |
| SCHEMBL1784442 | 0.85 | TAAR1 (0.60) | ATML3MBTL1DRD4DRD2DRD3 | |
| SCHEMBL7702938 | 0.83 | HDAC1 (0.43) | — | |
| Hydrochloric Acid SCHEMBL30624645 | 0.83 | TAAR1 (0.58) | ATML3MBTL1DRD4DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696140-A | FOR TREATMENT OF ASTHMA, ALLERGIES, NERVOUS SYSTEM DISORDERS OR CANCER | LEO PHARMACEUTICAL PRODUCTS LTD. (DK) | 1997-12-09 | — | — | US | disclosed |