SCHEMBL2147268

SCHEMBL2147268

NCCCCOc1ccc(Br)cc1

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
DRD4 P21917 2/20 0.49
DRD2 P14416 1/20 0.49
DRD3 P35462 1/20 0.49
NOS1 P29475 2/20 0.47
KDM4E B2RXH2 2/20 0.46
RECQL P46063 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ITGB3 P05106 1/20 0.46
ITGA2B P08514 1/20 0.46
ALDH1A1 P00352 1/20 0.46
TAAR1 Q96RJ0 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8918756 0.98 ATM (0.50) ATML3MBTL1DRD4DRD2DRD3
SCHEMBL8432804 0.93 DRD4 (0.50) ATML3MBTL1DRD4DRD2DRD3
SCHEMBL17445905 0.89 ATM (0.60) ATML3MBTL1DRD4DRD2DRD3
SCHEMBL1784442 0.86 TAAR1 (0.60) ATML3MBTL1DRD4DRD2DRD3
SCHEMBL17465617 0.86 ATM (0.58) ATML3MBTL1DRD4DRD2DRD3
SCHEMBL7898603 0.86 ATM (0.58) ATML3MBTL1DRD4DRD2DRD3
SCHEMBL7679458 0.85 LSS (0.61) L3MBTL1ITGB3ITGA2B
Hydrochloric Acid SCHEMBL30624645 0.84 TAAR1 (0.58) ATML3MBTL1DRD4DRD2DRD3
SCHEMBL18235025 0.84 DRD4 (0.57) ATML3MBTL1DRD4DRD2DRD3
Hydrochloric Acid SCHEMBL7686335 0.83 LSS (0.60) L3MBTL1ITGB3ITGA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260063640-A1 Reagents for Directed Biomarker Signal Amplification SIRIGEN II LTD (GB) 2026-03-05 US disclosed
US-12345713-B2 Reagents for directed biomarker signal amplification SIRIGEN II LIMITED (GB) 2025-07-01 US disclosed
US-12253525-B2 Reagents for directed biomarker signal amplification SIRIGEN II LIMITED (GB) 2025-03-18 US disclosed
US-12241898-B2 Reagents for directed biomarker signal amplification SIRIGEN II LIMITED (GB) 2025-03-04 US disclosed
US-12235274-B2 Reagents for directed biomarker signal amplification SIRIGEN II LIMITED (GB) 2025-02-25 US disclosed
US-12153050-B2 Reagents for directed biomarker signal amplification SIRIGEN II LIMITED (GB) 2024-11-26 US disclosed
US-12111321-B2 Reagents for directed biomarker signal amplification SIRIGEN II LIMITED (GB) 2024-10-08 US disclosed
US-20240272166-A1 Novel Reagents for Directed Biomarker Signal Amplification SIRIGEN II LIMITED (GB) 2024-08-15 US disclosed
EP-2526138-B1 NOVEL REAGENTS FOR DIRECTED BIOMARKER SIGNAL AMPLIFICATION SIRIGEN II LTD (GB) 2024-02-28 EP disclosed
EP-3981819-B1 NOVEL REAGENTS FOR DIRECTED BIOMARKER SIGNAL AMPLIFICATION SIRIGEN II LTD (GB) 2024-02-28 EP disclosed
US-20120252986-A1 SIGNAL AMPLIFIED BIOLOGICAL DETECTION WITH CONJUGATED POLYMERS NATIONAL UNIVERSITY OF SINGAPORE (SG) 2012-10-04 US disclosed
US-20110256550-A1 Novel reagents for directed biomarker signal amplification SIRIGEN, INC. (US) 2011-10-20 US disclosed
US-20110257374-A1 Novel Reagents for Directed Biomarker Signal Amplification SIRIGEN, INC. (US) 2011-10-20 US disclosed
US-20110256549-A1 Novel reagents for directed biomarker signal amplification SIRIGEN, INC. (US) 2011-10-20 US disclosed
US-20110256549-A1 Novel reagents for directed biomarker signal amplification SIRIGEN, INC. (US) 2011-10-20 US disclosed
US-20110257374-A1 Novel Reagents for Directed Biomarker Signal Amplification SIRIGEN, INC. (US) 2011-10-20 US disclosed
WO-2011091086-A1 NOVEL REAGENTS FOR DIRECTED BIOMARKER SIGNAL AMPLIFICATION SIRIGEN INC. (US) 2011-07-28 WO disclosed
WO-2011091086-A1 NOVEL REAGENTS FOR DIRECTED BIOMARKER SIGNAL AMPLIFICATION SIRIGEN INC. (US) 2011-07-28 WO disclosed
WO-2010151807-A1 SIGNAL AMPLIFIED BIOLOGICAL DETECTION WITH CONJUGATED POLYMERS SIRIGEN, INC. (US) 2010-12-29 WO disclosed
WO-2010151807-A1 SIGNAL AMPLIFIED BIOLOGICAL DETECTION WITH CONJUGATED POLYMERS SIRIGEN, INC. (US) 2010-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12253525-B2 Reagents for directed biomarker signal amplification RNGTT, CAPG, CA14 ATM 3275/4885L3MBTL1 3113/4885DRD4 3548/4885
US-20110257374-A1 Novel Reagents for Directed Biomarker Signal Amplification RNGTT, CAPG, CD2BP2 ATM 3658/4885L3MBTL1 3469/4885DRD4 3716/4885
US-20110256549-A1 Novel reagents for directed biomarker signal amplification RNGTT, CAPG, CD2BP2 ATM 3658/4885L3MBTL1 3469/4885DRD4 3716/4885
US-12235274-B2 Reagents for directed biomarker signal amplification RNGTT, CAPG, CA14 ATM 3275/4885L3MBTL1 3113/4885DRD4 3548/4885
US-12345713-B2 Reagents for directed biomarker signal amplification RNGTT, CAPG, CA14 ATM 3275/4885L3MBTL1 3113/4885DRD4 3548/4885
US-12111321-B2 Reagents for directed biomarker signal amplification RNGTT, CAPG, CA14 ATM 3275/4885L3MBTL1 3113/4885DRD4 3548/4885
US-12241898-B2 Reagents for directed biomarker signal amplification RNGTT, CAPG, CA14 ATM 3275/4885L3MBTL1 3113/4885DRD4 3548/4885
US-20260063640-A1 Reagents for Directed Biomarker Signal Amplification RNGTT, RNMT, DNMT3L ATM 3723/4885L3MBTL1 61/4885DRD4 3669/4885
US-20240272166-A1 Novel Reagents for Directed Biomarker Signal Amplification RNGTT, CAPG, CD2BP2 ATM 3658/4885L3MBTL1 3469/4885DRD4 3716/4885
US-20110256550-A1 Novel reagents for directed biomarker signal amplification RNGTT, CAPG, CD2BP2 ATM 3658/4885L3MBTL1 3469/4885DRD4 3716/4885
US-12153050-B2 Reagents for directed biomarker signal amplification RNGTT, CAPG, CA14 ATM 3275/4885L3MBTL1 3113/4885DRD4 3548/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.