SCHEMBL8918878

SCHEMBL8918878

COc1ccc2c(c1)C(=N)NC21CCCOO1

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PDE7A Q13946 2/20 0.36
AKR1A1 P14550 1/20 0.33
AKR1B1 P15121 1/20 0.33
GRIN1 Q05586 1/20 0.32
GRIN2A Q12879 1/20 0.32
GRIN2B Q13224 1/20 0.32
KDM1A O60341 1/20 0.32
PDE3B Q13370 1/20 0.32
PDE3A Q14432 1/20 0.32
TDP2 O95551 1/20 0.32
ALDH1A1 P00352 1/20 0.31
CYP2C19 P33261 1/20 0.31
LRRK2 Q5S007 1/20 0.31
PDK2 Q15119 1/20 0.31
S1PR1 P21453 1/20 0.30
S1PR3 Q99500 1/20 0.30
EHMT2 Q96KQ7 1/20 0.30
ACHE P22303 1/20 0.30
METAP1 P53582 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8918879 0.90 PDE7A (0.39) PDE7AAKR1A1AKR1B1TDP2ALDH1A1
SCHEMBL8920391 0.87 CYP3A4 (0.36) ALDH1A1CYP2C19PDK2
SCHEMBL8921435 0.83 KDM4E (0.30)
SCHEMBL8920247 0.82 PDK2 (0.35) PDE3BPDE3AALDH1A1PDK2
SCHEMBL8922200 0.82 PDK2 (0.35) PDE3BPDE3AALDH1A1PDK2
SCHEMBL8919771 0.81 PDE7A (0.33) PDE7A
SCHEMBL8919829 0.80
SCHEMBL8920555 0.77 PDK2 (0.34) GRIN1GRIN2AGRIN2BALDH1A1CYP2C19
SCHEMBL8919838 0.77 ALDH1A1 (0.34) ALDH1A1
SCHEMBL8919595 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5691272-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-11-25 US disclosed
US-5559247-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1996-09-24 US disclosed
EP-0679640-A1 Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-11-02 EP disclosed