Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8368156 | 0.89 | GAA (0.76) | KMT2ANPSR1POLBLMNAGAA | |
| SCHEMBL17817424 | 0.89 | GAA (0.76) | KMT2ANPSR1POLBLMNAGAA | |
| SCHEMBL6594370 | 0.88 | KMT2A (0.75) | KMT2ANPSR1POLBLMNAGAA | |
| SCHEMBL6593284 | 0.87 | KMT2A (0.69) | KMT2ANPSR1POLBLMNAGAA | |
| SCHEMBL9095943 | 0.85 | POLB (0.64) | KMT2APOLBLMNAGAAALDH1A1 | |
| SCHEMBL5807392 | 0.84 | KMT2A (0.75) | KMT2ANPSR1POLBLMNAGAA | |
| SCHEMBL9316115 | 0.84 | POLB (0.69) | KMT2ANPSR1POLBLMNAGAA | |
| SCHEMBL1754877 | 0.84 | POLB (0.65) | KMT2ANPSR1POLBLMNAGAA | |
| SCHEMBL3757797 | 0.83 | KMT2A (0.73) | KMT2ANPSR1POLBLMNAGAA | |
| SCHEMBL20189628 | 0.83 | KMT2A (0.73) | KMT2ANPSR1POLBLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5605905-A | DIAZAQUINOMICIN ANALOGS | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 1997-02-25 | — | — | US | disclosed |
| EP-0574195-A1 | Antitumoral aza- and diazaanthracenes | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 1993-12-15 | — | — | EP | disclosed |