Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | GAA | P10253 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | RGS12 | O14924 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2875266 | 0.90 | KMT2A (0.68) | KMT2ANPSR1ALDH1A1GAAKDM4E | |
| SCHEMBL1494291 | 0.88 | ALDH1A1 (0.79) | KMT2AALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5807392 | 0.86 | KMT2A (0.75) | KMT2ANPSR1ALDH1A1GAAKDM4E | |
| SCHEMBL6594370 | 0.86 | KMT2A (0.75) | KMT2ANPSR1ALDH1A1GAAKDM4E | |
| SCHEMBL9316115 | 0.85 | POLB (0.69) | KMT2ANPSR1ALDH1A1GAAKDM4E | |
| SCHEMBL9468747 | 0.84 | KMT2A (0.82) | KMT2ANPSR1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL10684407 | 0.84 | SMN1; SMN2 (0.68) | KMT2AALDH1A1GAAPOLBMEN1 | |
| SCHEMBL17662314 | 0.84 | KMT2A (0.73) | KMT2ANPSR1ALDH1A1GAAKDM4E | |
| SCHEMBL20189628 | 0.84 | KMT2A (0.73) | KMT2ANPSR1ALDH1A1GAAKDM4E | |
| SCHEMBL5807397 | 0.84 | KMT2A (0.73) | KMT2ANPSR1ALDH1A1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12605468-B2 | Oxazine-based fluorophore compounds for nerve-specific imaging | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2026-04-21 | — | — | US | disclosed |
| US-20230148317-A1 | OXAZINE-BASED FLUOROPHORE COMPOUNDS FOR NERVE-SPECIFIC IMAGING | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2023-05-11 | — | — | US | disclosed |
| US-20230148317-A1 | OXAZINE-BASED FLUOROPHORE COMPOUNDS FOR NERVE-SPECIFIC IMAGING | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2023-05-11 | — | — | US | disclosed |
| US-20230148317-A1 | OXAZINE-BASED FLUOROPHORE COMPOUNDS FOR NERVE-SPECIFIC IMAGING | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2023-05-11 | — | — | US | disclosed |
| EP-4093443-A1 | OXAZINE-BASED FLUOROPHORE COMPOUNDS FOR NERVE-SPECIFIC IMAGING | Oregon Health & Science University (US) | 2022-11-30 | — | — | EP | disclosed |
| US-11492359-B2 | Near-infrared nerve-sparing fluorophores | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2022-11-08 | — | — | US | disclosed |
| US-20210317137-A1 | NEAR-INFRARED NERVE-SPARING FLUOROPHORES | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-10-14 | — | — | US | disclosed |
| US-20210317137-A1 | NEAR-INFRARED NERVE-SPARING FLUOROPHORES | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-10-14 | — | — | US | disclosed |
| US-20210236657-A1 | NERVE-SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-08-05 | — | — | US | disclosed |
| US-20210236657-A1 | NERVE-SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-08-05 | — | — | US | disclosed |
| WO-2016153242-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING CENTRAL NERVOUS SYSTEM DISEASE | 재단법인 경기과학기술진흥원 | 2016-09-29 | — | — | WO | disclosed |
| US-8679776-B2 | Activatable dyes | UNIVERSITY OF MASSACHUSETTS (US) | 2014-03-25 | — | — | US | disclosed |
| US-20100297684-A1 | ACTIVATIBLE DYES | UNIVERSITY OF MASSACHUSETTS | 2010-11-25 | — | — | US | disclosed |
| US-7528134-B2 | Acetamides and benzamides that are useful in treating sexual dysfunction | ABBOTT LABORATORIES INC. (US) | 2009-05-05 | — | — | US | disclosed |
| WO-2009036351-A2 | ACTIVATIBLE DYES | UNIVERSITY OF MASSACHUSETTS (US) | 2009-03-19 | — | — | WO | disclosed |
| US-20060009461-A1 | Acetamides and benzamides that are useful in treating sexual dysfunction | BHATIA PRAMILA A | 2006-01-12 | — | — | US | disclosed |
| EP-1509213-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | Abbott Laboratories (US) | 2005-03-02 | — | — | EP | disclosed |
| US-20040029887-A1 | Acetamides and benzamides that are useful in treating sexual dysfunction | ABBOTT LABORATORIES | 2004-02-12 | — | — | US | disclosed |
| US-20030229094-A1 | Acetamides and benzamides that are useful in treating sexual dysfunction | ABBOTT LABORATORIES | 2003-12-11 | — | — | US | disclosed |
| WO-2003099266-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | ABBOTT LABORATORIES (US) | 2003-12-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030229094-A1 | Acetamides and benzamides that are useful in treating sexual dysfunction | CATSPER1, CYP19A1, PDE12 | KMT2A 2169/4885NPSR1 1468/4885ALDH1A1 88/4885 |
| US-11492359-B2 | Near-infrared nerve-sparing fluorophores | NTRK1, PMP22, GAP43 | KMT2A 2855/4885NPSR1 460/4885ALDH1A1 813/4885 |
| US-20210236657-A1 | NERVE-SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION | PFAS, NPFFR2, NPFFR1 | KMT2A 3779/4885NPSR1 396/4885ALDH1A1 1305/4885 |
| US-20230148317-A1 | OXAZINE-BASED FLUOROPHORE COMPOUNDS FOR NERVE-SPECIFIC IMAGING | GAP43, NTRK1, CHAT | KMT2A 3803/4885NPSR1 1773/4885ALDH1A1 1300/4885 |
| US-20040029887-A1 | Acetamides and benzamides that are useful in treating sexual dysfunction | CATSPER1, CYP19A1, PDE12 | KMT2A 2169/4885NPSR1 1468/4885ALDH1A1 88/4885 |
| US-20060009461-A1 | Acetamides and benzamides that are useful in treating sexual dysfunction | PDE12, NAAA, CYP19A1 | KMT2A 1792/4885NPSR1 1595/4885ALDH1A1 193/4885 |
| US-20100297684-A1 | ACTIVATIBLE DYES | IK, MB, HMBS | KMT2A 2859/4885NPSR1 3872/4885ALDH1A1 856/4885 |
| US-12605468-B2 | Oxazine-based fluorophore compounds for nerve-specific imaging | CHRNB2, CHRNB3, CHRNB4 | KMT2A 4441/4885NPSR1 561/4885ALDH1A1 1339/4885 |
| US-20210317137-A1 | NEAR-INFRARED NERVE-SPARING FLUOROPHORES | NTRK1, NGF, SMN1; SMN2 | KMT2A 4578/4885NPSR1 878/4885ALDH1A1 822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.