SCHEMBL8918946

SCHEMBL8918946

CCOCCOC(=O)C(C)O[C]=O

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.48
ALDH1A1 P00352 2/20 0.48
THRB P10828 1/20 0.43
GAA P10253 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
HSD17B10 Q99714 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
KDM4E B2RXH2 1/20 0.33
ACACB O00763 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4681222 0.82 HCAR2 (0.35) TSHRALDH1A1TDP1HSD17B10
SCHEMBL1100387 0.82 ALDH1A1 (0.40) TSHRALDH1A1GAAHSD17B10L3MBTL1
SCHEMBL5143996 0.79 ALDH1A1 (0.47) TSHRALDH1A1TDP1L3MBTL1SMN1; SMN2
SCHEMBL10766086 0.79 ALDH1A1 (0.46) TSHRALDH1A1THRBHSD17B10
SCHEMBL9936746 0.79 ALDH1A1 (0.54) TSHRALDH1A1THRBGAATDP1
SCHEMBL9936438 0.79 ALDH1A1 (0.54) TSHRALDH1A1THRBGAATDP1
SCHEMBL7064771 0.77
SCHEMBL4676252 0.76 ALDH1A1 (0.60) TSHRALDH1A1THRBGAATDP1
SCHEMBL10233231 0.76 ALDH1A1 (0.60) TSHRALDH1A1THRBGAATDP1
SCHEMBL9714169 0.76 TSHR (0.50) TSHRALDH1A1THRBGAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5620944-A PRE- AND POST-EMERGENT WEED CONTROL NIHON NOHYAKU CO., LTD. (JP) 1997-04-15 US disclosed
EP-0590834-B1 Phenylimidazole derivatives, processes for production thereof, herbicides comprising said derivatives, and usages of said herbicides NIHON NOHYAKU CO LTD (JP) 1996-12-11 EP disclosed
EP-0590834-A1 Phenylimidazole derivatives, processes for production thereof, herbicides comprising said derivatives, and usages of said herbicides NIHON NOHYAKU CO., LTD. (JP) 1994-04-06 EP disclosed