Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16074744 | 0.97 | CYP4F2 (0.41) | CYP4F2CYP4A11SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL16077463 | 0.97 | CYP4F2 (0.41) | CYP4F2CYP4A11SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL6260682 | 0.97 | CYP4F2 (0.41) | CYP4F2CYP4A11SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL16074712 | 0.97 | CYP4F2 (0.41) | CYP4F2CYP4A11SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL16074916 | 0.97 | CYP4F2 (0.41) | CYP4F2CYP4A11SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL16074704 | 0.97 | CYP4F2 (0.41) | CYP4F2CYP4A11SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL16074887 | 0.97 | CYP4F2 (0.41) | CYP4F2CYP4A11SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL16074843 | 0.97 | CYP4F2 (0.41) | CYP4F2CYP4A11SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL16074924 | 0.97 | CYP4F2 (0.41) | CYP4F2CYP4A11SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL16074957 | 0.97 | CYP4F2 (0.41) | CYP4F2CYP4A11SMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686298-A | Enzymatic reduction method for the preparation of compounds useful for preparing taxanes | E. R. SQUIBB & SONS, INC. (US) | 1997-11-11 | — | — | US | disclosed |
| US-5420337-A | CHEMICAL INTERMEDIATES | E. R. SQUIBB & SONS, INC. (US) | 1995-05-30 | — | — | US | disclosed |