Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | AURKA | O14965 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.66 |
| ▸ | JAK2 | O60674 | 1/20 | 0.66 |
| ▸ | GMNN | O75496 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | EGFR | P00533 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | LYN | P07948 | 1/20 | 0.66 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | KIT | P10721 | 1/20 | 0.66 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Niclosamide SCHEMBL6662409 | 0.80 | KMT2A (1.00) | MEN1AURKANPC1PDPK1JAK2 | |
| Niclosamide SCHEMBL29363878 | 0.80 | KMT2A (1.00) | MEN1AURKANPC1PDPK1JAK2 | |
| Niclosamide SCHEMBL28313524 | 0.80 | KMT2A (1.00) | MEN1AURKANPC1PDPK1JAK2 | |
| Niclosamide SCHEMBL67182 | 0.80 | KMT2A (1.00) | MEN1AURKANPC1PDPK1JAK2 | |
| Niclosamide SCHEMBL27365268 | 0.80 | KMT2A (1.00) | MEN1AURKANPC1PDPK1JAK2 | |
| SCHEMBL8916846 | 0.80 | P2RX1 (0.66) | MEN1AURKANPC1PDPK1JAK2 | |
| SCHEMBL8042390 | 0.80 | KMT2A (0.81) | MEN1AURKANPC1PDPK1JAK2 | |
| SCHEMBL30771727 | 0.79 | KCNMA1 (0.76) | MEN1AURKANPC1PDPK1JAK2 | |
| SCHEMBL330387 | 0.79 | KCNMA1 (0.81) | MEN1AURKANPC1PDPK1JAK2 | |
| SCHEMBL15026045 | 0.79 | KCNMA1 (0.76) | MEN1AURKANPC1PDPK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656376-A | ANTI-FOULING, CAVITATION RESISTANCE, VIBRATION DAMPING | THE B. F. GOODRICH COMPANY (US) | 1997-08-12 | — | — | US | disclosed |
| US-5582528-A | Composite and fairwater structures for marine vessels | THE B. F. GOODRICH COMPANY (US) | 1996-12-10 | — | — | US | disclosed |
| US-5540173-A | Composite and fairwater structures for marine vessels | THE BF GOODRICH COMPANY (US) | 1996-07-30 | — | — | US | disclosed |
| EP-0710544-A2 | A laminate and a process for forming the same | THE B.F. GOODRICH COMPANY (US) | 1996-05-08 | — | — | EP | disclosed |
| US-5292270-A | Composite and fairwater structures for marine vessels | THE B. F. GOODRICH COMPANY (US) | 1994-03-08 | — | — | US | disclosed |
| EP-0528219-A2 | Composite and fairwater structures for marine vessels | THE B.F. GOODRICH COMPANY (US) | 1993-02-24 | — | — | EP | disclosed |