Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | TACR2 | P21452 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034268 | 1.00 | NR5A1 (0.57) | NR5A1LTA4HNPC1RAB9AMAPT | |
| SCHEMBL9510068 | 1.00 | NR5A1 (0.57) | NR5A1LTA4HNPC1RAB9AMAPT | |
| SCHEMBL9506148 | 0.85 | CYP2D6 (0.57) | NR5A1LTA4HNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9506174 | 0.85 | CYP2D6 (0.57) | NR5A1LTA4HNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7883759 | 0.83 | NR5A1 (0.56) | NR5A1LTA4HNPC1RAB9AMAPT | |
| SCHEMBL9228047 | 0.82 | NR5A1 (0.69) | NR5A1LTA4HNPC1RAB9AMAPT | |
| SCHEMBL10574379 | 0.82 | NR5A1 (0.69) | NR5A1LTA4HNPC1RAB9AMAPT | |
| SCHEMBL6255603 | 0.82 | NR5A1 (0.69) | NR5A1LTA4HNPC1RAB9AMAPT | |
| SCHEMBL9343934 | 0.82 | NR5A1 (0.69) | NR5A1LTA4HNPC1RAB9AMAPT | |
| SCHEMBL10337755 | 0.82 | NR5A1 (0.69) | NR5A1LTA4HNPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5651918-A | Optically active 1,3-dioxolane derivatives carrying a mesogenic radical in the 4-position, a process for their preparation and their use as doping agents in liquid-crystal mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-07-29 | — | — | US | disclosed |
| US-5384070-A | Use of optically active tetrahydrofuran-2-carboxylic acid esters as dopants in liquid-crystal mixtures, liquid-crystal mixtures containing same and novel optically active tetrahydrofuran-2-carboxylic acid esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-01-24 | — | — | US | disclosed |
| US-5380460-A | Ferroelectric liquid crystal compounds containing chiral haloalkoxy tail units and compositions containing them | DISPLAYTECH, INC. (US) | 1995-01-10 | — | — | US | disclosed |
| EP-0351746-B1 | Optically active 1,3-dioxolane derivatives containing a mesogene group in position 4, method for their preparation and their use as doping agents in liquid-crystal mixtures | HOECHST AG (DE) | 1993-12-29 | — | — | EP | disclosed |
| WO-1993020068-A1 | CHIRAL OXIRANE DERIVATIVES AND THEIR USE AS DOPING AGENTS IN LIQUID CRYSTAL MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-10-14 | — | — | WO | disclosed |
| WO-1993006192-A1 | FERROELECTRIC LIQUID CRYSTAL COMPOUNDS CONTAINING CHIRAL HALOALKOXY TAIL UNITS AND COMPOSITIONS CONTAINING THEM | DISPLAYTECH, INCORPORATED (US) | 1993-04-01 | — | — | WO | disclosed |
| EP-0355561-B1 | USE OF OPTICALLY ACTIVE TETRAHYDROFURAN-2-CARBOXYLIC-ACID ESTERS IN DOPING LIQUID-CRYSTAL MIXTURES, LIQUID-CRYSTAL MIXTURES CONTAINING THEM, AND OPTICALLY ACTIVE TETRAHYDROFURAN-2-CARBOXYLIC-ACID ESTERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-11-19 | — | — | EP | disclosed |
| EP-0438811-A2 | Esters of 3-halogeno- or 3-cyano-substituted 2-methylalkanecarboxylic acids and their use as doping agents in liquid-crystalline compositions | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-07-31 | — | — | EP | disclosed |
| EP-0355561-A1 | Use of optically active tetrahydrofuran-2-carboxylic-acid esters in doping liquid-crystal mixtures, liquid-crystal mixtures containing them, and optically active tetrahydrofuran-2-carboxylic-acid esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-02-28 | — | — | EP | disclosed |
| EP-0351746-A1 | Optically active 1,3-dioxolane derivatives containing a mesogene group in position 4, method for their preparation and their use as doping agents in liquid-crystal mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-01-24 | — | — | EP | disclosed |