Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | TACR2 | P21452 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034268 | 1.00 | NR5A1 (0.57) | NR5A1LTA4HNPC1RAB9AMAPT | |
| SCHEMBL8919072 | 1.00 | NR5A1 (0.57) | NR5A1LTA4HNPC1RAB9AMAPT | |
| SCHEMBL9506148 | 0.85 | CYP2D6 (0.57) | NR5A1LTA4HNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9506174 | 0.85 | CYP2D6 (0.57) | NR5A1LTA4HNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7883759 | 0.83 | NR5A1 (0.56) | NR5A1LTA4HNPC1RAB9AMAPT | |
| SCHEMBL9228047 | 0.82 | NR5A1 (0.69) | NR5A1LTA4HNPC1RAB9AMAPT | |
| SCHEMBL10574379 | 0.82 | NR5A1 (0.69) | NR5A1LTA4HNPC1RAB9AMAPT | |
| SCHEMBL6255603 | 0.82 | NR5A1 (0.69) | NR5A1LTA4HNPC1RAB9AMAPT | |
| SCHEMBL9343934 | 0.82 | NR5A1 (0.69) | NR5A1LTA4HNPC1RAB9AMAPT | |
| SCHEMBL10337755 | 0.82 | NR5A1 (0.69) | NR5A1LTA4HNPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295370-B1 | LIQUID-CRYSTALLINE 5-PHENYL PYRIMIDINE DERIVATIVES WITH AN SC OR SC (ASTERISK) PHASE, AND METHOD FOR PREPARING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-08-11 | — | — | EP | disclosed |
| US-4906752-A | Liquid-crystal 5-phenylpyrimidine derivatives having sc or sc* phases and a process for preparing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-03-06 | — | — | US | disclosed |