SCHEMBL8919227

SCHEMBL8919227

N=C1NC2(CCCOO2)c2ccc([N+](=O)[O-])cc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
TDP2 O95551 1/20 0.35
CAPN9 O14815 1/20 0.35
CASP3 P42574 1/20 0.35
ALDH1A1 P00352 2/20 0.34
PTPRC P08575 1/20 0.33
S100A4 P26447 1/20 0.33
MALT1 Q9UDY8 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
PGR P06401 3/20 0.32
EGFR P00533 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9091625 0.93 TDP1 (0.38) CYP3A4TDP1TDP2CAPN9CASP3
SCHEMBL8920380 0.91 TDP2 (0.38) CYP3A4TDP1TDP2CAPN9CASP3
SCHEMBL8919771 0.79 PDE7A (0.33)
SCHEMBL8918874 0.75 TDP1 (0.45) CYP3A4TDP1TDP2CAPN9CASP3
SCHEMBL8918907 0.71
SCHEMBL7830916 0.69 TDP1 (0.47) CYP3A4TDP1TDP2CAPN9CASP3
SCHEMBL8918880 0.68 TDP1 (0.40) CYP3A4TDP1TDP2CAPN9CASP3
SCHEMBL8918252 0.67 TDP2 (0.46) CYP3A4TDP1TDP2CAPN9CASP3
SCHEMBL29546694 0.67 TDP1 (0.59) CYP3A4TDP1TDP2CAPN9CASP3
SCHEMBL7816299 0.67 TDP1 (0.59) CYP3A4TDP1TDP2CAPN9CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5691272-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-11-25 US disclosed
US-5559247-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1996-09-24 US disclosed
EP-0679640-A1 Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-11-02 EP disclosed