SCHEMBL8919488

SCHEMBL8919488

Cc1cccc(NC(=O)NC2CC(c3cccc(F)c3)c3ccccc3N(CC(=O)NC(C)(C)C)C2=O)c1

nearest known ligand 0.87

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CCKBR P32239 20/20 0.87

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8920577 0.93 CCKBR (0.88) CCKBR
SCHEMBL8919483 0.93 CCKBR (0.84) CCKBR
SCHEMBL8920529 0.93 CCKBR (1.00) CCKBR
SCHEMBL8920741 0.92 CCKBR (0.83) CCKBR
SCHEMBL8920333 0.92 CCKBR (0.88) CCKBR
SCHEMBL8924370 0.92 CCKBR (0.85) CCKBR
SCHEMBL8920300 0.91 CCKBR (0.84) CCKBR
SCHEMBL8922434 0.91 CCKBR (0.84) CCKBR
SCHEMBL8920751 0.91 CCKBR (0.91) CCKBR
SCHEMBL8920674 0.91 CCKBR (0.92) CCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5643904-A Substituted hexahdryoazepinones and tetrahydrobenzazepinones PFIZER INC. (US) 1997-07-01 US disclosed
US-5484917-A FOR TREATMENT AND PREVENTION OF GASTROINTESTINAL DISORDERS, PAIN AND ANXIETY PFIZER INC. (US) 1996-01-16 US disclosed
WO-1993015059-A1 3-PHENYLUREIDO-AZEPIN-2-ONES AND -BENZAZEPIN-2-ONES USEFUL AS CHOLECYSTOKININ ANTAGONISTS PFIZER INC. (US) 1993-08-05 WO disclosed