Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 5/20 | 0.56 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.55 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.52 |
| ▸ | PDE5A | O76074 | 2/20 | 0.51 |
| ▸ | ACP1 | P24666 | 2/20 | 0.51 |
| ▸ | OGG1 | O15527 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.51 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.49 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.48 |
| ▸ | APP | P05067 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.47 |
| ▸ | CCR4 | P51679 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14256578 | 0.83 | MERTK (0.55) | MERTKCXCR4NPY5RPDE5AACP1 | |
| SCHEMBL27224034 | 0.80 | GBA1 (0.54) | MERTKCXCR4NPY5RPDE5AACP1 | |
| SCHEMBL14266658 | 0.79 | MERTK (0.52) | MERTKCXCR4NPY5RPDE5AACP1 | |
| SCHEMBL24649614 | 0.78 | NPY5R (0.79) | MERTKNPY5RPDE5AACP1OGG1 | |
| Hydrochloric Acid SCHEMBL8905933 | 0.77 | EHMT2 (0.54) | MERTKCXCR4NPY5RPDE5AACP1 | |
| SCHEMBL14256577 | 0.77 | MERTK (0.55) | MERTKCXCR4NPY5RPDE5AACP1 | |
| SCHEMBL30896224 | 0.76 | CXCR4 (0.63) | MERTKCXCR4NPY5RPDE5AACP1 | |
| SCHEMBL24649781 | 0.76 | CXCR4 (0.63) | MERTKCXCR4NPY5RPDE5AACP1 | |
| SCHEMBL1428308 | 0.76 | EHMT2 (0.70) | MERTKKDM1AEHMT2 | |
| SCHEMBL14266656 | 0.75 | MERTK (0.71) | MERTKCXCR4NPY5RPDE5AACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020821-A1 | HETEROARYL DERIVATIVES | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |