Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.54 |
| ▸ | MERTK | Q12866 | 8/20 | 0.53 |
| ▸ | KDM1A | O60341 | 2/20 | 0.53 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.53 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.53 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.52 |
| ▸ | PDE5A | O76074 | 2/20 | 0.51 |
| ▸ | ACP1 | P24666 | 2/20 | 0.51 |
| ▸ | OGG1 | O15527 | 1/20 | 0.51 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.47 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.47 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8919640 | 0.80 | MERTK (0.56) | MERTKKDM1AEHMT2CXCR4NPY5R | |
| SCHEMBL14256578 | 0.79 | MERTK (0.55) | GBA1MERTKKDM1AEHMT2CXCR4 | |
| SCHEMBL24649614 | 0.78 | NPY5R (0.79) | GBA1MERTKNPY5RPDE5AACP1 | |
| Hydrochloric Acid SCHEMBL8905933 | 0.77 | EHMT2 (0.54) | MERTKKDM1AEHMT2CXCR4NPY5R | |
| SCHEMBL24649781 | 0.76 | CXCR4 (0.63) | MERTKEHMT2CXCR4NPY5RPDE5A | |
| SCHEMBL30896224 | 0.76 | CXCR4 (0.63) | MERTKEHMT2CXCR4NPY5RPDE5A | |
| SCHEMBL23260475 | 0.76 | EHMT2 (0.68) | KDM1AEHMT2SLC2A1RCOR1 | |
| SCHEMBL16280668 | 0.75 | NPY5R (0.62) | GBA1MERTKNPY5RPDE5AACP1 | |
| SCHEMBL14266664 | 0.75 | APP (0.62) | MERTKEHMT2CXCR4NPY5RPDE5A | |
| SCHEMBL27224041 | 0.75 | MERTK (0.61) | GBA1MERTKCXCR4NPY5RPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240166626-A1 | Compounds and Methods for Preventing, Treating, or Ameliorating Airway Disease | UNIV JEFFERSON (US) | 2024-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240166626-A1 | Compounds and Methods for Preventing, Treating, or Ameliorating Airway Disease | ADRB2, ADRB1, ADRB3 | GBA1 3401/4885MERTK 3423/4885KDM1A 3832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.