SCHEMBL8919712

SCHEMBL8919712

Fc1cc(F)c(F)c(F)c1F.Fc1ccc(N(F)F)c(F)c1F

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
EPHX2 P34913 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL135331 0.91 CES2 (0.37) CES2CES1EPHX2
Iodide SCHEMBL28981860 0.88 CES2 (0.36) CES2CES1EPHX2
Hydrochloric Acid SCHEMBL28694543 0.88 CES2 (0.36) CES2CES1EPHX2
Hydrochloric Acid SCHEMBL28243615 0.86 CES2 (0.34) CES2CES1EPHX2
Hydrochloric Acid SCHEMBL28572396 0.86 CES2 (0.34) CES2CES1EPHX2
Hydrochloric Acid SCHEMBL28572399 0.86 CES2 (0.34) CES2CES1EPHX2
Hydrochloric Acid SCHEMBL28243616 0.86 CES2 (0.34) CES2CES1EPHX2
Hydrochloric Acid SCHEMBL28244299 0.86 CES2 (0.34) CES2CES1EPHX2
Hydrochloric Acid SCHEMBL28244298 0.86 CES2 (0.34) CES2CES1EPHX2
SCHEMBL28169856 0.84 CES2 (0.33) CES2CES1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5679879-A CONVERTING SUBSTITUTED ANILINE TO DIAZONIUM SALT IN PRESENCE OF HYPOPHOSPHOROUS ACID OR SALT THEREOF, STRONG ACID, METAL CATALYST, SO THAT DIAZONIUM GROUP IS REPLACED BY HYDROGEN AS IT IS FORMED RHONE-POULENC CHEMICALS LIMITED (GB) 1997-10-21 US disclosed