Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NOS1 | P29475 | 1/20 | 0.50 |
| ▸ | HMOX2 | P30519 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469882 | 0.93 | MAOB (0.56) | MAOBRAB9AHTTL3MBTL1ALDH1A1 | |
| SCHEMBL5263425 | 0.90 | MAOB (0.61) | MAOBRAB9AHTTL3MBTL1ALDH1A1 | |
| SCHEMBL7162438 | 0.88 | MAOB (0.62) | MAOBRAB9AHTTL3MBTL1ALDH1A1 | |
| SCHEMBL2801030 | 0.86 | MAOB (0.60) | MAOBRAB9AHTTL3MBTL1ALDH1A1 | |
| SCHEMBL13883739 | 0.86 | MAOB (0.64) | MAOBRAB9AHTTL3MBTL1ALDH1A1 | |
| SCHEMBL30395305 | 0.82 | MAOB (0.56) | MAOBRAB9AHTTL3MBTL1ALDH1A1 | |
| SCHEMBL3792473 | 0.82 | MAOB (0.56) | MAOBRAB9AHTTL3MBTL1ALDH1A1 | |
| SCHEMBL307767 | 0.82 | MAOB (0.56) | MAOBRAB9AHTTL3MBTL1ALDH1A1 | |
| SCHEMBL1547536 | 0.82 | MAOB (0.60) | MAOBRAB9AHTTL3MBTL1ALDH1A1 | |
| SCHEMBL23071123 | 0.81 | ALDH1A1 (0.55) | MAOBRAB9AHTTL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024088189-A1 | MACROCYCLIC COMPOUND AS CDK9 INHIBITOR AND USE THEREOF | 科辉智药生物科技（无锡）有限公司 | 2024-05-02 | — | — | WO | disclosed |
| US-5591751-A | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-07 | — | — | US | disclosed |
| EP-0636128-A1 | PIPERAZINOCARBONYLCARBOSTYRILS AS PERIPHERAL VASODILATORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-01 | — | — | EP | disclosed |
| WO-1994019339-A1 | PIPERAZINOCARBONYLCARBOSTYRILS AS PERIPHERAL VASODILATORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-01 | — | — | WO | disclosed |