Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | MGAM | O43451 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SI | P14410 | 2/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11056301 | 0.87 | TSHR (0.53) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL30888816 | 0.85 | TSHR (0.50) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL5283413 | 0.80 | TSHR (0.48) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL534516 | 0.80 | — | — | |
| SCHEMBL30786366 | 0.79 | — | — | |
| SCHEMBL19730844 | 0.78 | CYP2D6 (0.60) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL2690145 | 0.78 | MGAM (0.52) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL8892963 | 0.78 | TSHR (0.43) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL10788950 | 0.77 | TSHR (0.48) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL9517329 | 0.77 | TSHR (0.48) | TSHRHSD17B10MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633379-A | N-METHYLASPARTIC ACID ANTAGONIST | CIBA-GEIGY CORPORATION (US) | 1997-05-27 | — | — | US | disclosed |
| US-4130565-A | 3-ALKYL-TETRAHYDROPYRAN-OR THIOPYRAN-2,4-DIONES AS CHEMICAL INTERMEDIATES | SHIONOGI & CO., LTD. (JP) | 1978-12-19 | — | — | US | disclosed |