Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.40 |
| ▸ | STAT3 | P40763 | 2/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8924547 | 0.89 | STAT3 (0.40) | MMP2STAT3CYP2C9ALDH1A1KMT2A | |
| SCHEMBL30130355 | 0.73 | STAT3 (0.43) | MMP2STAT3ANPEPCYP3A4CYP2C9 | |
| SCHEMBL30636832 | 0.73 | STAT3 (0.43) | MMP2STAT3ANPEPCYP3A4CYP2C9 | |
| SCHEMBL21822929 | 0.73 | STAT3 (0.43) | MMP2STAT3ANPEPCYP3A4CYP2C9 | |
| SCHEMBL1482389 | 0.72 | ALDH1A1 (0.49) | STAT3CYP2C9PKMALDH1A1KMT2A | |
| SCHEMBL21987511 | 0.72 | ALDH1A1 (0.49) | STAT3CYP2C9PKMALDH1A1KMT2A | |
| SCHEMBL8258339 | 0.72 | ALDH1A1 (0.49) | STAT3CYP2C9PKMALDH1A1KMT2A | |
| SCHEMBL8640816 | 0.72 | CA1 (0.41) | MMP2STAT3ANPEPCYP3A4CYP2C9 | |
| SCHEMBL8314106 | 0.70 | STAT3 (0.35) | STAT3CYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL17709993 | 0.70 | STAT3 (0.39) | STAT3CYP3A4CYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684137-A | TECHNETIUM AND RHENIUM LABELS FOR LIGANDS AND PROTEINS | NEORX CORPORATION (US) | 1997-11-04 | — | — | US | disclosed |
| US-5252721-A | S3 N chelating compounds | NEORX CORPORATION (US) | 1993-10-12 | — | — | US | disclosed |