SCHEMBL8920033

SCHEMBL8920033

C=COC(C(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.57
CYP3A4 P08684 3/20 0.57
TDP1 Q9NUW8 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
LMNA P02545 4/20 0.48
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
POLB P06746 2/20 0.48
MAPT P10636 2/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.43
AKT1 P31749 1/20 0.42
NPSR1 Q6W5P4 3/20 0.41
ADRB2 P07550 1/20 0.40
CYP2C19 P33261 3/20 0.40
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9248607 0.84 ALDH1A1 (0.59) ALDH1A1CYP3A4TDP1L3MBTL1LMNA
SCHEMBL19305342 0.83 CYP2C19 (0.47) ALDH1A1CYP3A4LMNACES2CES1
SCHEMBL159213 0.81 ALDH1A1 (0.69) ALDH1A1CYP3A4TDP1L3MBTL1LMNA
SCHEMBL2363249 0.79 ALDH1A1 (0.54) ALDH1A1CYP3A4TDP1L3MBTL1LMNA
SCHEMBL30552449 0.79 ALDH1A1 (0.58) ALDH1A1CYP3A4TDP1L3MBTL1LMNA
SCHEMBL37125 0.79 ALDH1A1 (0.63) ALDH1A1CYP3A4TDP1L3MBTL1LMNA
SCHEMBL30283 0.79 ALDH1A1 (0.67) ALDH1A1CYP3A4TDP1L3MBTL1LMNA
Water SCHEMBL5357502 0.78 ALDH1A1 (0.61) ALDH1A1CYP3A4TDP1L3MBTL1LMNA
SCHEMBL30398 0.78 ALDH1A1 (0.53) ALDH1A1CYP3A4TDP1L3MBTL1LMNA
Water SCHEMBL9512888 0.77 ALDH1A1 (0.65) ALDH1A1CYP3A4TDP1L3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0020473-A1 PHOSPHINE ACTIVATED PHOTOSENSITIVE COMPOSITIONS AND PHOTOPOLYMER PRINTING PLATES MADE THEREFROM. NAPP SYSTEMS INC (US) 1981-01-07 EP claimed
US-4233391-A PRINTING PLATES NAPP SYSTEMS (USA) INC. (US) 1980-11-11 US claimed
EP-0020473-A4 PHOSPHINE ACTIVATED PHOTOSENSITIVE COMPOSITIONS AND PHOTOPOLYMER PRINTING PLATES MADE THEREFROM. NAPP SYSTEMS INC (US) 1980-10-16 EP claimed
WO-1980000623-A1 PHOSPHINE ACTIVATED PHOTOSENSITIVE COMPOSITIONS AND PHOTOPOLYMER PRINTING PLATES MADE THEREFROM NAPP SYSTEMS INC (US) 1980-04-03 WO claimed
US-4042386-A WATER DEVELOPABLE, PHOTOPOLYMERIZABLE NAPP SYSTEMS (US) 1977-08-16 US claimed
US-5683837-A AMINE ADDITION POLYMER, UNSATURATED MONOMER, PHOTOINITIATOR NAPP SYSTEMS, INC. (US) 1997-11-04 US disclosed
WO-1996018133-A1 HIGH-RESOLUTION LETTERPRESS PRINTING PLATES AND WATER-SOLUBLE PHOTOPOLYMERIZABLE COMPOSITIONS COMPRISING A POLYVINYLALCOHOL DERIVATIVE USEFUL THEREFOR NAPP SYSTEMS, INC. (US) 1996-06-13 WO disclosed
US-4540649-A Water developable photopolymerizable composition and printing plate element containing same NAPP SYSTEMS (USA) INC. (US) 1985-09-10 US disclosed
EP-0020473-A1 PHOSPHINE ACTIVATED PHOTOSENSITIVE COMPOSITIONS AND PHOTOPOLYMER PRINTING PLATES MADE THEREFROM. NAPP SYSTEMS INC (US) 1981-01-07 EP disclosed
US-4233391-A PRINTING PLATES NAPP SYSTEMS (USA) INC. (US) 1980-11-11 US disclosed
EP-0020473-A4 PHOSPHINE ACTIVATED PHOTOSENSITIVE COMPOSITIONS AND PHOTOPOLYMER PRINTING PLATES MADE THEREFROM. NAPP SYSTEMS INC (US) 1980-10-16 EP disclosed
WO-1980000623-A1 PHOSPHINE ACTIVATED PHOTOSENSITIVE COMPOSITIONS AND PHOTOPOLYMER PRINTING PLATES MADE THEREFROM NAPP SYSTEMS INC (US) 1980-04-03 WO disclosed
US-4116715-A Method for removing photopolymers from metal substrates SMIGGEN FRANK J 1978-09-26 US disclosed
US-4042386-A WATER DEVELOPABLE, PHOTOPOLYMERIZABLE NAPP SYSTEMS (US) 1977-08-16 US disclosed