Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8923489 | 0.97 | KDM4E (0.50) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8920155 | 0.94 | KDM4E (0.54) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8920123 | 0.86 | KDM4E (0.52) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8923424 | 0.86 | KDM4E (0.69) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8924304 | 0.84 | GRIN1 (0.46) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL8921130 | 0.84 | MAPT (0.50) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8921296 | 0.82 | KDM4E (0.67) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8921390 | 0.82 | KDM4E (0.67) | KDM4EALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL8919874 | 0.81 | GSK3B (0.55) | KDM4EALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL8919961 | 0.81 | GRIN1 (0.44) | KDM4EALDH1A1GRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633379-A | N-METHYLASPARTIC ACID ANTAGONIST | CIBA-GEIGY CORPORATION (US) | 1997-05-27 | — | — | US | claimed |
| JP-8041027-A | — | — | None | — | — | JP | disclosed |
| US-5633379-A | N-METHYLASPARTIC ACID ANTAGONIST | CIBA-GEIGY CORPORATION (US) | 1997-05-27 | — | — | US | disclosed |
| JP-H0841027-A | 3-HETEROALIPHATIC-AND 3-HETERO(ARYL)ALIPHATIC-2(IH)-QUINOLONE DERIVATIVE | CIBA GEIGY AG | 1996-02-13 | — | — | JP | disclosed |